200937-57-1

200937-57-1 structure
200937-57-1 structure
  • Name: n-(9-fluorenylmethoxycarbonyl)-l-leucin&
  • Chemical Name: N-(9-Fluorenylmethoxycarbonyl)-L-leucine-15N
  • CAS Number: 200937-57-1
  • Molecular Formula: C21H2315NO4
  • Molecular Weight: 354.41
  • Catalog: Biochemical Amino acids and their derivatives Leucine derivative
  • Create Date: 2018-12-29 20:28:34
  • Modify Date: 2024-01-05 20:58:36
  • Fmoc-leucine-15N is a 15N-labeled and 13C-labled EIDD-1931. EIDD-1931 (Beta-d-N4-hydroxycytidine; NHC) is a novel nucleoside analog and behaves as a potent anti-virus agent. EIDD-1931 effectively inhibits the replication activity of venezuelan equine ence

Name N-(9-Fluorenylmethoxycarbonyl)-L-leucine-15N
Synonyms L-Leucine-15N,N-Fmoc
Fmoc-Leu-OH-15N
MFCD00209748
Description Fmoc-leucine-15N is a 15N-labeled and 13C-labled EIDD-1931. EIDD-1931 (Beta-d-N4-hydroxycytidine; NHC) is a novel nucleoside analog and behaves as a potent anti-virus agent. EIDD-1931 effectively inhibits the replication activity of venezuelan equine ence
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[75].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-242.

[2]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-242.

Melting Point 152-156ºC(lit.)
Molecular Formula C21H2315NO4
Molecular Weight 354.41
Exact Mass 354.16000
PSA 75.63000
LogP 4.41530
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi
RIDADR NONH for all modes of transport
WGK Germany 3