2668267-47-6

2668267-47-6 structure

Name: DPP
Chemical Name: DPP
CAS Number: 2668267-47-6
Molecular Formula: C₃₆H₄₀Cl₂N₂O₁₀Pt
Molecular Weight: 926.70
Catalog: Signaling Pathways Apoptosis Apoptosis
Create Date: 2023-11-19 16:14:21
Modify Date: 2026-07-01 18:40:44
DPP is a Platinum(IV) complex, bearing pterostilbene-derived axial ligand. DPP inhibit the JAK2-STAT3 pathway in breast cancer (BC) cells with antiproliferative activity, and activates caspase-3 and cleaved poly ADP-ribose polymerase to induces apoptosis. DPP promotes the maturation and antigen presentation of dendritic cells, and exhibits in vivo safety[1].

Name	DPP
Synonyms	Platinum, diamminedichlorobis[2-[4-[(1E)-2-(3,5-dimethoxyphenyl)ethenyl]phenoxy]acetato-κO]-, (OC-6-33)

Description	DPP is a Platinum(IV) complex, bearing pterostilbene-derived axial ligand. DPP inhibit the JAK2-STAT3 pathway in breast cancer (BC) cells with antiproliferative activity, and activates caspase-3 and cleaved poly ADP-ribose polymerase to induces apoptosis. DPP promotes the maturation and antigen presentation of dendritic cells, and exhibits in vivo safety[1].
Related Catalog	Signaling Pathways >> Stem Cell/Wnt >> STAT Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Signaling Pathways >> JAK/STAT Signaling >> JAK Signaling Pathways >> Epigenetics >> JAK Signaling Pathways >> Stem Cell/Wnt >> JAK Signaling Pathways >> JAK/STAT Signaling >> STAT
References	[1]. Cai L, et al. Platinum(IV) Complexes as Inhibitors of STAT3 and Regulators of the Tumor Microenvironment To Control Breast Cancer. J Med Chem. 2023 Aug 24;66(16):11351-11364.

Molecular Formula	C₃₆H₄₀Cl₂N₂O₁₀Pt
Molecular Weight	926.70