2377372-62-6

2377372-62-6 structure

Name: MTP
Chemical Name: MTP
CAS Number: 2377372-62-6
Molecular Formula: C₂₉H₂₃F₃N₄O₂
Molecular Weight: 516.51
Catalog: Signaling Pathways Apoptosis Apoptosis
Create Date: 2024-07-16 21:02:39
Modify Date: 2025-08-25 13:59:30
MTP is a PKM2 inhibitor. MTP induces cancer cell apoptosis by modulating caspase-3 activation. MTP induces autophagy and increases ROS generation. MTP also inhibits JAK2 signaling. MTP can be used for research of oral squamous cell carcinoma[1].

Name	MTP

Description	MTP is a PKM2 inhibitor. MTP induces cancer cell apoptosis by modulating caspase-3 activation. MTP induces autophagy and increases ROS generation. MTP also inhibits JAK2 signaling. MTP can be used for research of oral squamous cell carcinoma[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Signaling Pathways >> JAK/STAT Signaling >> JAK Signaling Pathways >> Epigenetics >> JAK Signaling Pathways >> Stem Cell/Wnt >> JAK Signaling Pathways >> Autophagy >> Autophagy
Target	JAK2
References	[1]. Weng JR, et al. A PKM2 inhibitor induces apoptosis and autophagy through JAK2 in human oral squamous cell carcinoma cells. Chem Biol Interact. 2023 Aug 1;380:110538.

Molecular Formula	C₂₉H₂₃F₃N₄O₂
Molecular Weight	516.51