210980-68-0

210980-68-0 structure

Name: Dehydrosimvastatin
Chemical Name: [(1S,3R,7S,8S,8aR)-3,7-dimethyl-8-[2-[(2R)-6-oxo-2,3-dihydropyran-2-yl]ethyl]-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] 2,2-dimethylbutanoate
CAS Number: 210980-68-0
Molecular Formula: C₂₅H₃₆O₄
Molecular Weight: 400.551
Catalog: Research Areas Others
Create Date: 2018-06-25 11:36:33
Modify Date: 2025-08-23 18:40:17
Anhydrosimvastatin (Impurity C) is an impurity of Simvastatin. Simvastatin is a competitive inhibitor of HMG-CoA reductase[1].

Name	[(1S,3R,7S,8S,8aR)-3,7-dimethyl-8-[2-[(2R)-6-oxo-2,3-dihydropyran-2-yl]ethyl]-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] 2,2-dimethylbutanoate
Synonyms	Butanoic acid, 2,2-dimethyl-, (1S,3R,7S,8S,8aR)-8-[2-[(2R)-3,6-dihydro-6-oxo-2H-pyran-2-yl]ethyl]-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-1-naphthalenyl ester anhydrosimvastatin (1S,3R,7S,8S,8aR)-3,7-Dimethyl-8-{2-[(2R)-6-oxo-3,6-dihydro-2H-pyran-2-yl]ethyl}-1,2,3,7,8,8a-hexahydro-1-naphthalenyl 2,2-dimethylbutanoate Dehydrosimvastatin Dehydro Simvastatin Anhydro-simvastatin Simvastatin EP Impurity C Dehydrosimvastatin Simvastatin Impurity 3

Description	Anhydrosimvastatin (Impurity C) is an impurity of Simvastatin. Simvastatin is a competitive inhibitor of HMG-CoA reductase[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. IOANA DRĂGHICI, et al. DEVELOPMENT OF A NEW LC METHOD FOR THE IDENTIFICATION, SEPARATION AND ASSAY OF SIMVASTATIN AND ITS IMPURITIES. FARMACIA, 2013, Vol. 61, 2.

Hazard Codes	Xi
RIDADR	NONH for all modes of transport

145576-25-6

~4%

210980-68-0

79902-63-9

121009-77-6

Literature: WO2005/40107 A2, ; Page/Page column 31-32; 61-62 ;

145576-24-5

850920-00-2

81189-92-6

29138-64-5

151006-15-4

Detail

Literature: WO2005/40107 A2, ; Page/Page column 51-53 ;

145576-25-6

210980-68-0

Literature: WO2005/40107 A2, ; Page/Page column 73-74 ;

145576-24-5

5856-77-9

~12%

210980-68-0

145576-25-6

Detail

Literature: WO2005/40107 A2, ; Page/Page column 45; 83 ;

145576-24-5

29138-64-5

~0%

210980-68-0

850920-00-2

Detail

Literature: WO2005/40107 A2, ; Page/Page column 41-43; 80-82 ;

79902-63-9

210980-68-0

Literature: WO2005/40107 A2, ; Page/Page column 75-76 ;