Shanghai Nianxing Industrial Co., Ltd
China
Product Name: ABBV-712
Price: Check
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: ABBV-712
Price: ￥Inquiry/100mg ￥Inquiry/250mg ￥Inquiry/1g
Purity: 98.0%
Stocking Period: 10 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

2368945-27-9

2368945-27-9 structure

2368945-27-9 structure

Name: ABBV-712
Chemical Name: ABBV-712
CAS Number: 2368945-27-9
Molecular Formula: C₂₄H₂₈N₄O₅
Molecular Weight: 452.50
Catalog: Signaling Pathways Epigenetics JAK
Create Date: 2024-01-14 01:09:08
Modify Date: 2024-01-14 01:09:08
ABBV-712 is a selective inhibitor of Tyrosine kinase 2 (TYK2), with IC50 of 0.195 μM, that play important role in autoimmune diseases[1].

Name	ABBV-712

Description	ABBV-712 is a selective inhibitor of Tyrosine kinase 2 (TYK2), with IC50 of 0.195 μM, that play important role in autoimmune diseases[1].
Related Catalog	Signaling Pathways >> JAK/STAT Signaling >> JAK Signaling Pathways >> Epigenetics >> JAK Signaling Pathways >> Stem Cell/Wnt >> JAK Research Areas >> Inflammation/Immunology
Target	JAK1:80 μM (IC50)
References	[1]. Eric Breinlinger, et al. Targeting the Tyrosine Kinase 2 (TYK2) Pseudokinase Domain: Discovery of the Selective TYK2 Inhibitor ABBV-712. J Med Chem. 2023 Oct 26;66(20):14335-14356.

Molecular Formula	C₂₄H₂₈N₄O₅
Molecular Weight	452.50

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