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2755325-84-7

2755325-84-7 structure

2755325-84-7 structure

Name: HDAC/JAK/BRD4-IN-1
Chemical Name: HDAC/JAK/BRD4-IN-1
CAS Number: 2755325-84-7
Molecular Formula: C₂₄H₂₈N₆O₃
Molecular Weight: 448.52
Catalog: Signaling Pathways Apoptosis Apoptosis
Create Date: 2024-02-12 10:44:07
Modify Date: 2025-09-27 15:57:19
HDAC/JAK/BRD4-IN-1(compound 25ap) is a potent HDAC/JAK/BRD4 triple inhibitor. HDAC/JAK/BRD4-IN-1 inhibit cell growth and induces apoptosis in MDA-MB-231 cells, and shows anticancer activity in vivo[1].

Name	HDAC/JAK/BRD4-IN-1

Description	HDAC/JAK/BRD4-IN-1(compound 25ap) is a potent HDAC/JAK/BRD4 triple inhibitor. HDAC/JAK/BRD4-IN-1 inhibit cell growth and induces apoptosis in MDA-MB-231 cells, and shows anticancer activity in vivo[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Signaling Pathways >> JAK/STAT Signaling >> JAK Signaling Pathways >> Epigenetics >> JAK Signaling Pathways >> Stem Cell/Wnt >> JAK Signaling Pathways >> Cell Cycle/DNA Damage >> HDAC Signaling Pathways >> Epigenetics >> HDAC Signaling Pathways >> Epigenetics >> Epigenetic Reader Domain
References	[1]. Zhao C, et al. Discovery of Novel Fedratinib-Based HDAC/JAK/BRD4 Triple Inhibitors with Remarkable Antitumor Activity against Triple Negative Breast Cancer [published online ahead of print, 2023 Oct 5]. J Med Chem. 2023;10.1021/acs.jmedchem.3c01242.

Molecular Formula	C₂₄H₂₈N₆O₃
Molecular Weight	448.52

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