Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Palmitic acid
Price: Check
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

2068766-90-3

2068766-90-3 structure

2068766-90-3 structure

Name: JAK-IN-34
Chemical Name: JAK-IN-34
CAS Number: 2068766-90-3
Molecular Formula: C₂₇H₂₆N₆O
Molecular Weight: 450.53
Catalog: Signaling Pathways Epigenetics JAK
Create Date: 2024-01-13 14:03:08
Modify Date: 2024-01-13 14:03:08
JAK-IN-34 (compound 11n) is a potent against of JAKs with IC50 values of 0.40, 0.83, 2.10, 1.95 nM target JAK1, JAK2, JAK3, TYK2, respectively. JAK-IN-34 reduces joint swelling with good safety[1].

Name	JAK-IN-34

Description	JAK-IN-34 (compound 11n) is a potent against of JAKs with IC50 values of 0.40, 0.83, 2.10, 1.95 nM target JAK1, JAK2, JAK3, TYK2, respectively. JAK-IN-34 reduces joint swelling with good safety[1].
Related Catalog	Signaling Pathways >> JAK/STAT Signaling >> JAK Signaling Pathways >> Epigenetics >> JAK Signaling Pathways >> Stem Cell/Wnt >> JAK Research Areas >> Inflammation/Immunology
Target	JAK1:0.40 nM (IC50) JAK2:0.83 nM (IC50) JAK3:2.10 nM (IC50) Tyk2:1.95 nM (IC50)
References	[1]. Jinbao Xiang, et al. Design, synthesis, and pharmacological evaluation of quinazoline derivatives as novel and potent pan-JAK inhibitors. Bioorg Chem. 2023.

Molecular Formula	C₂₇H₂₆N₆O
Molecular Weight	450.53

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.