3000541-95-4

3000541-95-4 structure

3000541-95-4 structure

Name: ROCK2-IN-7
Chemical Name: ROCK2-IN-7
CAS Number: 3000541-95-4
Molecular Formula: C₂₆H₂₈FN₅O
Molecular Weight: 445.53
Catalog: Signaling Pathways Cell Cycle/DNA Damage ROCK
Create Date: 2023-12-22 16:15:20
Modify Date: 2024-01-17 15:35:34
ROCK2-IN-7 is a kinase inhibitor targeting to ROCK2. ROCK2-IN-7 inhibits ROCK2/pSTAT3 Signaling. ROCK2-IN-7 suppresses systemic immunity activation and attenuates inflammation in psoriasis model[1].

Name	ROCK2-IN-7

Description	ROCK2-IN-7 is a kinase inhibitor targeting to ROCK2. ROCK2-IN-7 inhibits ROCK2/pSTAT3 Signaling. ROCK2-IN-7 suppresses systemic immunity activation and attenuates inflammation in psoriasis model[1].
Related Catalog	Signaling Pathways >> Stem Cell/Wnt >> STAT Signaling Pathways >> JAK/STAT Signaling >> STAT Research Areas >> Others Signaling Pathways >> Cell Cycle/DNA Damage >> ROCK Signaling Pathways >> Metabolic Enzyme/Protease >> MMP Signaling Pathways >> Stem Cell/Wnt >> ROCK Signaling Pathways >> TGF-beta/Smad >> ROCK
Target	ROCK2 MMP-2 Stat-3
References	[1]. Huang, Yun, et al. "Design, Synthesis, and Biological Evaluation of an Orally Bioavailable, Potent, and Selective ROCK2 Inhibitor for Psoriasis Treatment." Journal of Medicinal Chemistry (2023)

Molecular Formula	C₂₆H₂₈FN₅O
Molecular Weight	445.53