2966790-98-5

2966790-98-5 structure

Name: Tubulin polymerization-IN-56
Chemical Name: Tubulin polymerization-IN-56
CAS Number: 2966790-98-5
Molecular Formula: C₂₂H₂₂ClN₃O₃
Molecular Weight: 411.88
Catalog: Signaling Pathways Apoptosis Apoptosis
Create Date: 2024-02-04 11:23:03
Modify Date: 2024-02-04 11:23:03
Tubulin polymerization-IN-56 (compound 8l), an indazole derivative, is a potent tubulin polymerization inhibitor through interacting with the colchicine site, resulting in cell cycle arrest and cellular apoptosis. polymerization-IN-56 reduces cell migration and leads to more potent inhibition of tumor growth in vivo[1].

Name	Tubulin polymerization-IN-56

Description	Tubulin polymerization-IN-56 (compound 8l), an indazole derivative, is a potent tubulin polymerization inhibitor through interacting with the colchicine site, resulting in cell cycle arrest and cellular apoptosis. polymerization-IN-56 reduces cell migration and leads to more potent inhibition of tumor growth in vivo[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Microtubule/Tubulin Signaling Pathways >> Cytoskeleton >> Microtubule/Tubulin
References	[1]. Ying-Jie Cui, et al. The discovery of water-soluble indazole derivatives as potent microtubule polymerization inhibitors. Eur J Med Chem. 2023 Oct 18:262:115870.

Molecular Formula	C₂₂H₂₂ClN₃O₃
Molecular Weight	411.88