Tubulin polymerization-IN-56

Modify Date: 2024-02-04 11:23:03

Tubulin polymerization-IN-56 structure	Common Name	Tubulin polymerization-IN-56
	CAS Number	2966790-98-5	Molecular Weight	411.88
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₂H₂₂ClN₃O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Tubulin polymerization-IN-56

Tubulin polymerization-IN-56 (compound 8l), an indazole derivative, is a potent tubulin polymerization inhibitor through interacting with the colchicine site, resulting in cell cycle arrest and cellular apoptosis. polymerization-IN-56 reduces cell migration and leads to more potent inhibition of tumor growth in vivo[1].

Name	Tubulin polymerization-IN-56

Description	Tubulin polymerization-IN-56 (compound 8l), an indazole derivative, is a potent tubulin polymerization inhibitor through interacting with the colchicine site, resulting in cell cycle arrest and cellular apoptosis. polymerization-IN-56 reduces cell migration and leads to more potent inhibition of tumor growth in vivo[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Microtubule/Tubulin Signaling Pathways >> Cytoskeleton >> Microtubule/Tubulin
References	[1]. Ying-Jie Cui, et al. The discovery of water-soluble indazole derivatives as potent microtubule polymerization inhibitors. Eur J Med Chem. 2023 Oct 18:262:115870.

Molecular Formula	C₂₂H₂₂ClN₃O₃
Molecular Weight	411.88

Tubulin polymerization-IN-56

Use of Tubulin polymerization-IN-56

Names

Tubulin polymerization-IN-56 Biological Activity

Chemical & Physical Properties