225120-65-0

225120-65-0 structure

Name: Cathepsin Inhibitor 1
Chemical Name: 3-Chloro-N-(cyanomethyl)-Nα-{[1-methyl-3-(2-methyl-2-propanyl)-1H -pyrazol-5-yl]carbonyl}-L-phenylalaninamide
CAS Number: 225120-65-0
Molecular Formula: C₂₀H₂₄ClN₅O₂
Molecular Weight: 401.89000
Catalog: Biochemical Inhibitor Proteases Cysteine Protease Inhibitor
Create Date: 2018-09-19 20:56:53
Modify Date: 2024-01-11 10:40:21
Cathepsin inhibitor 1 (compound 25) is a potent and selective inhibitor of Cathepsin, with pIC50s of 7.9, 6.7, 6.0, 5.5 and 5.2 for CatL, CatL2, CatS, CatK, and CatB, respectively[1].

Name	3-Chloro-N-(cyanomethyl)-Nα-{[1-methyl-3-(2-methyl-2-propanyl)-1H -pyrazol-5-yl]carbonyl}-L-phenylalaninamide
Synonyms	Cathepsin Inhibitor 1

Description	Cathepsin inhibitor 1 (compound 25) is a potent and selective inhibitor of Cathepsin, with pIC50s of 7.9, 6.7, 6.0, 5.5 and 5.2 for CatL, CatL2, CatS, CatK, and CatB, respectively[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> Cathepsin
References	[1]. Asaad N, et, al. Dipeptidyl nitrile inhibitors of Cathepsin L. Bioorg Med Chem Lett. 2009 Aug 1;19(15):4280-3.

HS Code	29242990