957-77-7

957-77-7 structure

Name: 5-Hydroxyuridine
Chemical Name: 5-hydroxyuridine
CAS Number: 957-77-7
Molecular Formula: C₉H₁₂N₂O₇
Molecular Weight: 260.20
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2018-05-28 08:00:00
Modify Date: 2024-01-10 18:43:32
5-Hydroxyuridine (OHUrd) is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	5-hydroxyuridine
Synonyms	5-Hydroxy-uridin 5-Hydroxy-uracil-ribotid Uridine, 5-hydroxy- Uridine,5-hydroxy 5-hydroxy-uridine 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-methylol-tetrahydrofuran-2-yl]-5-hydroxy-pyrimidine-2,4-quinone 5-Hydroxyuridine 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-hydroxy-pyrimidine-2,4-dione

Description	5-Hydroxyuridine (OHUrd) is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog Research Areas >> Others
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

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957-77-7

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