957-77-7
957-77-7 structure
- Name: 5-Hydroxyuridine
- Chemical Name: 5-hydroxyuridine
- CAS Number: 957-77-7
- Molecular Formula: C9H12N2O7
- Molecular Weight: 260.20
- Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
- Create Date: 2018-05-28 08:00:00
- Modify Date: 2026-07-08 15:50:43
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5-Hydroxyuridine (OHUrd) is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
| Name | 5-hydroxyuridine |
|---|---|
| Synonyms |
Isobbituridine
5-Hydroxyuridine, isobbituri dine,RNA-modified nucleoside ho5U, anticancer agent 5-HYDROXYURIDINE 5-Hydroxy-uridin 5-Hydroxy-uracil-ribotid Uridine, 5-hydroxy 5-Hydroxyuridine, isobbituridine 1-[(2R,3R,4S,5R)-3,4-DIHYDROXY-5-(HYDROXYMETHYL)OXOLAN-2-YL]-5-HYDROXY-3H-PYRIMIDINE-2,4-DIONE 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-hydroxypyrimidine-2,4(1H,3H)-dione 1-beta-D-Ribofuranosylisobbituric acid Uridine,5-hydroxy 5-hydroxy-uridine 1-(β-D-Ribofuranosyl)-5-hydroxypyrimidine-2,4(1H,3H)-dione 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-methylol-tetrahydrofuran-2-yl]-5-hydroxy-pyrimidine-2,4-quinone 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-hydroxy-pyrimidine-2,4-dione 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-hydroxypyrimidine-2,4-dione |
| Description | 5-Hydroxyuridine (OHUrd) is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
|---|---|
| Related Catalog | |
| References |
| Density | 1.8±0.1 g/cm3 |
|---|---|
| Molecular Formula | C9H12N2O7 |
| Molecular Weight | 260.20 |
| Exact Mass | 260.064453 |
| PSA | 145.01000 |
| LogP | -1.51 |
| Index of Refraction | 1.698 |
| Storage condition | 2-8°C |
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957-77-7
Detail
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| Literature: Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, , vol. 40, # 9 p. 768 - 775 |
