957-75-5
957-75-5 structure
- Name: 5-Bromouridine
- Chemical Name: 5-bromouridine
- CAS Number: 957-75-5
- Molecular Formula: C9H11BrN2O6
- Molecular Weight: 323.10
- Catalog: Biochemical Nucleoside drugs Nucleoside intermediate
- Create Date: 2018-05-06 08:00:00
- Modify Date: 2026-06-30 19:55:21
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5-Bromouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
| Name | 5-bromouridine |
|---|---|
| Synonyms |
5-Bromo-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3
5-bromo-uridin 5-Br-rU 5-Bromouridine //BP 5-Bromouracil ribonucleoside 5-Bromo-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione 5-bromouracil-1-β-d-ribofuranoside 5-BrU ()-5-Bromouridine 5-Bromouracil-1-β-D-ribofuranoside, 5-Bromouridine 5-BROMOURIDINE extrapure 5-BROMOURACIL-1-BETA-D-RIBOFURANOSIDE 5-BROMOURIDINE (5-BROMOURACIL-1-β-D-RIBOFURANOSIDE: 5-BRU) 5-BroMo-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxyMethyl)tetrahydrofuran-2-yl)pyriMidine-2,4(1H,3H)-dione 5-Bromouracil-1-β-D-ribofuranoside 5-BROMO-URIDINE(5-BRU) 5-bromo-UMP MFCD00006528 1-β-ribofuranosyl-5-bromo-uracil (-)-5-BROMOURIDINE 5-BROMOURIDINE EINECS 213-486-6 5-broMo-1-[(2S,3S,4R,5S)-3,4-dihydroxy-5-(hydroxyMethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyriMidine-2,4-dione 5-Br-Ur bromouridine 5-broMo-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxyMethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyriMidine-2,4-dione 5-Br-Uridine 5'-BROMOURIDINE 1-beta-ribofuranosyl-5-bromo-uracil Uridine, 5-bromo 5-Bromouridine > 5-Bromo-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)pyrimidine-2,4(1 5-Bromo-D-uridine |
| Description | 5-Bromouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
|---|---|
| Related Catalog | |
| References |
| Density | 2.0±0.1 g/cm3 |
|---|---|
| Melting Point | 180-182 °C (dec.)(lit.) |
| Molecular Formula | C9H11BrN2O6 |
| Molecular Weight | 323.10 |
| Exact Mass | 321.980042 |
| PSA | 124.78000 |
| LogP | -0.92 |
| Index of Refraction | 1.691 |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
|
| Hazard Codes | Xn |
|---|---|
| Safety Phrases | S22-S24/25 |
| WGK Germany | 3 |
| RTECS | YU7300000 |
|
~97%
957-75-5 |
| Literature: Kumar; Wiebe; Knaus Canadian Journal of Chemistry, 1994 , vol. 72, # 9 p. 2005 - 2010 |
|
~85%
957-75-5 |
| Literature: Asakura, Jun-ichi; Robins, Morris J. Journal of Organic Chemistry, 1990 , vol. 55, # 16 p. 4928 - 4933 |
|
~58%
957-75-5 |
| Literature: Synthesis, , vol. No. 9, p. 829 - 831 |
|
~%
957-75-5 |
| Literature: Journal of Organic Chemistry, , vol. 55, # 16 p. 4928 - 4933 |
|
~%
957-75-5 |
| Literature: Bioorganic and Medicinal Chemistry, , vol. 20, # 24 p. 7184 - 7193 |
|
~%
957-75-5 |
| Literature: Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, , vol. 40, # 9 p. 768 - 775 |
| Precursor 5 | |
|---|---|
| DownStream 7 | |
