124-48-1

124-48-1 structure

Name: DIBROMOCHLOROMETHANE
Chemical Name: chlorodibromomethane
CAS Number: 124-48-1
Molecular Formula: CHBr₂Cl
Molecular Weight: 208.280
Catalog: Organic raw materials Hydrocarbon compounds and their derivatives Hydrocarbon halide
Create Date: 2018-03-20 08:00:00
Modify Date: 2026-07-08 16:48:49

Name	chlorodibromomethane
Synonyms	Dibromochloromethane,0.2 mg/mL in MeOH Dibromomonochloromethane chlorodibromo-methan DIBROMOCHLOROMETHANE OEKANAL, AMYLENE Dibromochloromethane (1mg/ml in Methanol) [for Water Analysis] ChlorodibroMoMethane standd Dibronochloromethane Dibromochloromethane standd solution Dibromochloromethane ( with Ethanol) Cdbm CHClBr2 CHLORODIBROMOMETHANE methane,dibromochloro Dibromochloromethane(stabilizedwithEthanol)> NCI-C55254 DIBROMOCHLOROMETHANE, 1000MG, NEAT Dibromochloromethane,Chlorodibromomethane 1,2-Dibromochloromethane dibromochloromethane solution Chlorodibromomethane, in Certan bottle MFCD00000820 Dibromochloromethane in Methanol Dibromo(chloro)methane Dibromochloromethane Standd EINECS 204-704-0 Methane, chlorodibromo DIBROMOCHLOROMETHANE, 1X1ML, MEOH, 200UG /ML dibromochloro-methan CHLORODIBROMOMETHANE ISO 9001：2015 REACH Dibromochloromethane Standd Solution (1mg/ml Hexane Solution) Chlorodibromomethane [-1] Chlorodibromomethane ( with Ethanol) DibroMochloroMethane Chlorobromoform Monochlorodibromomethane Chlorodibromomethane in methanol

Density	2.5±0.1 g/cm3
Boiling Point	117.1±8.0 °C at 760 mmHg
Melting Point	−22 °C(lit.)
Molecular Formula	CHBr₂Cl
Molecular Weight	208.280
Flash Point	19.8±8.5 °C
Exact Mass	205.813339
LogP	2.20
Vapour Pressure	21.0±0.2 mmHg at 25°C
Index of Refraction	1.562

CHEMICAL IDENTIFICATION

RTECS NUMBER :: PA6360000

CHEMICAL NAME :: Methane, chlorodibromo-

CAS REGISTRY NUMBER :: 124-48-1

BEILSTEIN REFERENCE NO. :: 1731046

LAST UPDATED :: 199710

DATA ITEMS CITED :: 27

MOLECULAR FORMULA :: C-H-Br2-Cl

MOLECULAR WEIGHT :: 208.29

WISWESSER LINE NOTATION :: GYEE

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 370 mg/kg

TOXIC EFFECTS :: Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Behavioral - somnolence (general depressed activity) Behavioral - tremor

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 800 mg/kg

TOXIC EFFECTS :: Brain and Coverings - changes in circulation (hemorrhage, thrombosis, etc.) Liver - fatty liver degeneration Blood - hemorrhage

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 14 gm/kg/14D-I

TOXIC EFFECTS :: Liver - other changes Kidney, Ureter, Bladder - other changes Related to Chronic Data - death

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 10 gm/kg/4W-C

TOXIC EFFECTS :: Liver - changes in liver weight Kidney, Ureter, Bladder - changes in bladder weight Nutritional and Gross Metabolic - weight loss or decreased weight gain

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 8568 mg/kg/9W-I

TOXIC EFFECTS :: Blood - changes in erythrocyte (RBC) count Nutritional and Gross Metabolic - weight loss or decreased weight gain Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - transaminases

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 16250 mg/kg/13W-I

TOXIC EFFECTS :: Liver - fatty liver degeneration Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis) Related to Chronic Data - death

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 3500 mg/kg/14D-C

TOXIC EFFECTS :: Liver - changes in liver weight Endocrine - changes in spleen weight Nutritional and Gross Metabolic - weight loss or decreased weight gain

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 52500 mg/kg/2Y-C

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors

TYPE OF TEST :: Cytogenetic analysis

TYPE OF TEST :: Mutation test systems - not otherwise specified

TYPE OF TEST :: Sister chromatid exchange

MUTATION DATA

TYPE OF TEST :: Sex chromosome loss and nondisjunction

TEST SYSTEM :: Rodent - hamster Lung

DOSE/DURATION :: 720 mg/L

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 369,243,1996 *** REVIEWS *** IARC Cancer Review:Animal Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 52,243,1991 IARC Cancer Review:Human Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 52,243,1991 IARC Cancer Review:Group 3 IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 52,243,1991

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302
Precautionary Statements	P260-P280-P301 + P310-P311
Personal Protective Equipment	Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	Xn:Harmful;
Risk Phrases	R22;R36/37/38;R40
Safety Phrases	S45-S36/37/39-S26-S36/37
RIDADR	2810
WGK Germany	3
RTECS	PA6360000
Packaging Group	III
HS Code	2903799090

Precursor 9
127-09-3 67-66-3 75-25-2 74-87-3
34557-54-5 142-28-9 627-30-5 41036-93-5
75-27-4
DownStream 10
125013-86-7 125013-87-8 542-92-7 108-90-7
119-64-2 83692-65-3 83692-67-5 826-73-3
83692-66-4 83692-63-1

HS Code	2903799090
Summary	2903799090 halogenated derivatives of acyclic hydrocarbons containing two or more different halogens。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

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