58735-64-1

58735-64-1 structure
58735-64-1 structure
  • Name: isoroquefortine C
  • Chemical Name: roquefortine c
  • CAS Number: 58735-64-1
  • Molecular Formula: C22H23N5O2
  • Molecular Weight: 389.450
  • Catalog: Signaling Pathways Anti-infection Bacterial
  • Create Date: 2018-07-02 14:45:38
  • Modify Date: 2024-01-16 11:21:32
  • Roquefortine C, a fungal cyclopeptide isolated from Penicillium roquefortii, activates P-gp and also inhibits P450-3A and other haemoproteins. Roquefortine C has bacteriostatic activities against Gram-positive bacteria[1].

Name roquefortine c
Synonyms isoroquefortine C
roquefortine from penicillium*roqueforti
10b-(1,1-dimethyl-allyl)-3-(1(3)H-imidazol-4-ylmethylene)-2,3,6,10b,11,11a-hexahydro-5aH-pyrazino[1',2':1,5]pyrrolo[2,3-b]indole-1,4-dione
2H-Pyrazino[1',2':1,5]pyrrolo[2,3-b]indole-1,4(3H,5aH)-dione, 10b-(1,1-dimethyl-2-propen-1-yl)-6,10b,11,11a-tetrahydro-3-(1H-imidazol-5-ylmethylene)-, (3Z,5aS,10bR,11aS)-
(3Z,5aS,10bR,11aS)-3-(1H-Imidazol-5-ylmethylene)-10b-(2-methyl-3-buten-2-yl)-6,10b,11,11a-tetrahydro-2H-pyrazino[1',2':1,5]pyrrolo[2,3-b]indole-1,4(3H,5aH)-dione
2H-Pyrazino[1',2':1,5]pyrrolo[2,3-b]indole-1,4(3H,5aH)-dione
isoroquefortine
Roquefortin
PYRAZINO1215PYRROLO23BINDOLE143H5AH
RORIFONE
ROQUEFORTINE
Description Roquefortine C, a fungal cyclopeptide isolated from Penicillium roquefortii, activates P-gp and also inhibits P450-3A and other haemoproteins. Roquefortine C has bacteriostatic activities against Gram-positive bacteria[1].
Related Catalog
References

[1]. García-Rico RO, et al. Effect of a heterotrimeric G protein alpha subunit on conidia germination, stress response, and roquefortine C production in Penicillium roqueforti. Food Addit Contam. 2005 Apr;22(4):361-8.

Density 1.4±0.1 g/cm3
Boiling Point 768.3±60.0 °C at 760 mmHg
Molecular Formula C22H23N5O2
Molecular Weight 389.450
Flash Point 418.4±32.9 °C
Exact Mass 389.185181
PSA 90.12000
LogP 1.40
Vapour Pressure 0.0±2.6 mmHg at 25°C
Index of Refraction 1.687

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UQ4730500
CAS REGISTRY NUMBER :
58735-64-1
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C22-H23-N5-O2
MOLECULAR WEIGHT :
389.50

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
15 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
EXPEAM Experientia. (Birkhaeuser Verlag, POB 133, CH-4010 Basel, Switzerland) V.1- 1945- Volume(issue)/page/year: 32,140,1976
Risk Phrases 23/24/25
Safety Phrases 22-36/37/39-45
RIDADR UN 2811 6.1/PG 2
HS Code 2933990090
HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%