isoroquefortine C structure
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Common Name | isoroquefortine C | ||
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CAS Number | 58735-64-1 | Molecular Weight | 389.450 | |
Density | 1.4±0.1 g/cm3 | Boiling Point | 768.3±60.0 °C at 760 mmHg | |
Molecular Formula | C22H23N5O2 | Melting Point | N/A | |
MSDS | Chinese USA | Flash Point | 418.4±32.9 °C |
Use of isoroquefortine CRoquefortine C, a fungal cyclopeptide isolated from Penicillium roquefortii, activates P-gp and also inhibits P450-3A and other haemoproteins. Roquefortine C has bacteriostatic activities against Gram-positive bacteria[1]. |
Name | roquefortine c |
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Synonym | More Synonyms |
Description | Roquefortine C, a fungal cyclopeptide isolated from Penicillium roquefortii, activates P-gp and also inhibits P450-3A and other haemoproteins. Roquefortine C has bacteriostatic activities against Gram-positive bacteria[1]. |
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Related Catalog | |
References |
Density | 1.4±0.1 g/cm3 |
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Boiling Point | 768.3±60.0 °C at 760 mmHg |
Molecular Formula | C22H23N5O2 |
Molecular Weight | 389.450 |
Flash Point | 418.4±32.9 °C |
Exact Mass | 389.185181 |
PSA | 90.12000 |
LogP | 1.40 |
Vapour Pressure | 0.0±2.6 mmHg at 25°C |
Index of Refraction | 1.687 |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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Risk Phrases | 23/24/25 |
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Safety Phrases | 22-36/37/39-45 |
RIDADR | UN 2811 6.1/PG 2 |
HS Code | 2933990090 |
HS Code | 2933990090 |
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Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Novel key metabolites reveal further branching of the roquefortine/meleagrin biosynthetic pathway.
J. Biol. Chem. 288(52) , 37289-95, (2013) Metabolic profiling and structural elucidation of novel secondary metabolites obtained from derived deletion strains of the filamentous fungus Penicillium chrysogenum were used to reassign various pre... |
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Determination of selected mycotoxins in mould cheeses with liquid chromatography coupled to tandem with mass spectrometry.
Food Addit. Contam. 22(5) , 449-56, (2005) A simple and feasible method is described for analysing nine mycotoxins in cheese matrix. The method involves liquid extraction followed by high performance liquid chromatographic separation and mass ... |
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A single cluster of coregulated genes encodes the biosynthesis of the mycotoxins roquefortine C and meleagrin in Penicillium chrysogenum.
Chem. Biol. 18(11) , 1499-512, (2011) A single gene cluster of Penicillium chrysogenum contains genes involved in the biosynthesis and secretion of the mycotoxins roquefortine C and meleagrin. Five of these genes have been silenced by RNA... |
isoroquefortine C |
roquefortine from penicillium*roqueforti |
10b-(1,1-dimethyl-allyl)-3-(1(3)H-imidazol-4-ylmethylene)-2,3,6,10b,11,11a-hexahydro-5aH-pyrazino[1',2':1,5]pyrrolo[2,3-b]indole-1,4-dione |
2H-Pyrazino[1',2':1,5]pyrrolo[2,3-b]indole-1,4(3H,5aH)-dione, 10b-(1,1-dimethyl-2-propen-1-yl)-6,10b,11,11a-tetrahydro-3-(1H-imidazol-5-ylmethylene)-, (3Z,5aS,10bR,11aS)- |
(3Z,5aS,10bR,11aS)-3-(1H-Imidazol-5-ylmethylene)-10b-(2-methyl-3-buten-2-yl)-6,10b,11,11a-tetrahydro-2H-pyrazino[1',2':1,5]pyrrolo[2,3-b]indole-1,4(3H,5aH)-dione |
2H-Pyrazino[1',2':1,5]pyrrolo[2,3-b]indole-1,4(3H,5aH)-dione |
isoroquefortine |
Roquefortin |
PYRAZINO1215PYRROLO23BINDOLE143H5AH |
RORIFONE |
ROQUEFORTINE |