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110044-82-1

110044-82-1 structure

110044-82-1 structure

Name: Calpain Inhibitor I
Chemical Name: acetylleucyl-leucyl-norleucinal
CAS Number: 110044-82-1
Molecular Formula: C₂₀H₃₇N₃O₄
Molecular Weight: 383.526
Catalog: Biochemical Inhibitor Proteases Cysteine Protease Inhibitor
Create Date: 2018-06-23 18:43:41
Modify Date: 2026-07-09 17:17:45
MG-101 is a potent inhibitor of cysteine proteases which inhibits calpain I, calpain II, cathepsin B and cathepsin L with Kis of 190, 220, 150 and 500 pM, respectively.

Name	acetylleucyl-leucyl-norleucinal
Synonyms	AC-LEU-LEU-NLE-ALDEHYDE L-Leucinamide, N-acetyl-L-leucyl-N-[(1S)-1-formylpentyl] N-acetyl-L-leucyl-N-[(1S)-1-formylpentyl]-L-Leucinamide CALPAIN INHIBITOR I N-Acetyl-L-leucinyl-L-leucinyl-L-norleucinal ac-llnl-cho CALPAIN INHIBITOR I;AC-LLNL-CHO;ALLN InSolution ALLN - - Calbiochem AC-LEU-LEU-L-NORLEUCINAL LLNL ALLN (DMSO solution) (S)-2-acetamido-N-((S)-1-amino-4-methyl-1-oxopentan-2-yl)-4-methyl-N-((S)-1-oxohexan-2-yl)pentanamide Ac-Leu-Leu-Nle-H AC-LL-NORLEUCINAL MG-101 (ALLN) AC-LEU-LEU-NORLEUCINAL ALLN - - Calbiochem MG-101 (Calpain inhibitor I MG 101 AC-LEU-LEU-NLE-CHO N-Acetyl-Leu-Leu-Norleu-al N-Acetyl-Leu-Leu-Norleu-al, N-Acetyl-L-leucyl-L-leucyl-L-norleucinal CALPAIN INHIBITOR N-ACETYL-LEU-LEU-NLE-CHO ACETYL-LEU-LEU-NORLEUCINAL ACETYL-L-LEUCYL-L-LEUCYL-L-NORLEUCINAL N-Acetyl-L-leucine-L-leucine-L-norleucinal N-Acetyl-L-leucyl-N-[(2S)-1-oxohexan-2-yl]-L-leucinamide ALLN Ac-LLnL-CHO MG-101 N-Acetyl-Leu-Leu-Norleu-al N-Acetyl-L-leucyl-L-leucyl-L-norleucinal ALLN, Ac-LLnL-CHO, MG-101, N-Acetyl-Leu-Leu-Norleu-al, N-Acetyl-L-leucyl-L-leucyl-L-norleucinal Ac-Leu-Leu-Nle-al Calpain Inhibitor I,ALLN AC-LEU-LEU-NLE-H (ALDEHYDE) N-Acetyl-L-leucyl-N-((1S)-1-formylpentyl)-L-leucinamide N-ACETYL-L-LEUCYL-L-LEUCYL-L-NORLEUCINAL MG-101, 10 mM in DMSO InSolution ALLN N-AC-LEU-LEU-NORLEUCINAL ALLN, cysteine proteinase inhibitor MFCD00065505 RKO,MG-101,colon cancer,Bax,HG2,Proteasome,MG 101,Inhibitor,mitochondria,HCT116,inhibit,Apoptosis,SW480,anti-tumor MG-101 (ALLN) ，S7386 Ac-LLnL-CHO, ALLN, MG-101, N-Acetyl-Leu-Leu-Norleu-al, N-Acetyl-L-leucyl-L-leucyl-L-norleucinal Calpain Inhibitor Ⅰ 〔N-Acetyl-L-leucyl-L-leucyl-L-norleucinal〕 N-ACETYL-LEU-LEU-NORLEUCINAL ALLN N-Acetyl-L-leucyl-N-[(2S)-1-oxo-2-hexanyl]-L-leucinamide CALPAIN INHIBITOR-1;MG101;MG-101;MG Calpain Inhibitor I, ALLN

Description	MG-101 is a potent inhibitor of cysteine proteases which inhibits calpain I, calpain II, cathepsin B and cathepsin L with Kis of 190, 220, 150 and 500 pM, respectively.
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Proteasome Research Areas >> Cancer
References	[1]. Li SZ, et al. ALLN hinders HCT116 tumor growth through Bax-dependent apoptosis. Biochem Biophys Res Commun. 2013 Jul 26;437(2):325-330.

Density	1.0±0.1 g/cm3
Boiling Point	632.2±50.0 °C at 760 mmHg
Molecular Formula	C₂₀H₃₇N₃O₄
Molecular Weight	383.526
Flash Point	192.9±30.3 °C
Exact Mass	383.278412
PSA	104.37000
LogP	3.37
Appearance	powder \| white
Vapour Pressure	0.0±1.9 mmHg at 25°C
Index of Refraction	1.474
Storage condition	−20°C
Water Solubility	DMSO: soluble \| Soluble in dimethyl sulfoxide, ethanol, methanol. Insoluble in water, and aqueous buffers.

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Safety Phrases	22-24/25
RIDADR	NONH for all modes of transport
WGK Germany	3

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