DC Chemicals Limited
China
Product Name: PF-152
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

1112169-64-8

1112169-64-8 structure

1112169-64-8 structure

Name: PF-152
Chemical Name: N-(4-Fluoro-3-methoxybenzyl)-6-(2-{[(2S,5R)-5-(hydroxymethyl)-1,4 -dioxan-2-yl]methyl}-2H-tetrazol-5-yl)-2-methyl-4-pyrimidinecarbo xamide
CAS Number: 1112169-64-8
Molecular Formula: C₂₁H₂₄FN₇O₅
Molecular Weight: 473.45800
Create Date: 2016-11-04 20:15:19
Modify Date: 2024-01-11 20:42:05
PF-152 is a potent, highly selective and orally bioavailable MMP13 inhibitor with Ki of 1.5 nM, with no activity against MMP3 (Ki>10 uM).

Name	N-(4-Fluoro-3-methoxybenzyl)-6-(2-{[(2S,5R)-5-(hydroxymethyl)-1,4 -dioxan-2-yl]methyl}-2H-tetrazol-5-yl)-2-methyl-4-pyrimidinecarbo xamide
Synonyms	PF-152

Molecular Formula	C₂₁H₂₄FN₇O₅
Molecular Weight	473.45800
Exact Mass	473.18200
PSA	146.40000
LogP	0.68340

1112179-15-3 structure

1112179-15-3

1112178-44-5 structure

1112178-44-5

~25%

1112169-64-8 structure

1112169-64-8

Literature: PFIZER INC. Patent: WO2009/16498 A1, 2009 ; Location in patent: Page/Page column 152-153 ; WO 2009/016498 A1

Precursor 2
1112179-15-3 1112178-44-5
DownStream 0