1762-34-1

1762-34-1 structure

Name: Xeglyze
Chemical Name: 5-methyl-2-(5-methylpyridin-2-yl)pyridine
CAS Number: 1762-34-1
Molecular Formula: C₁₂H₁₂N₂
Molecular Weight: 184.237
Catalog: Pharmaceutical intermediate Heterocyclic compound Pyridine compound Pyridine derivative
Create Date: 2018-07-20 13:11:57
Modify Date: 2024-01-04 18:14:04
Abametapir is a metalloproteinase (MMP) inhibitor which is able to target metalloproteinases critical to egg hatching and louse development. Abametapir can inhibit hatching of both head and body louse[1][2].

Name	5-methyl-2-(5-methylpyridin-2-yl)pyridine
Synonyms	5,5'-Dimethyl-2,2'-bipyridyl 5,5′-dimethyl-2,2′-bipyridine 5,5'-dimethyl-bpy 5,5'-Dimethyl-2,2'-dipyridyl 5,5'-dimethyl-2,2'-bipy 6,6'-Di-3-picoline MFCD01740554 5,5'-dimethyl-2,2'-bispyridine Xeglyze 2,2'-BIPYRIDINE,5,5'-DIMETHYL 6,6'-Di-3-picolyl 5,5'-Dimethyl-2,2'-bipyridine 2,2'-Bipyridine, 5,5'-dimethyl- abametapir

Description	Abametapir is a metalloproteinase (MMP) inhibitor which is able to target metalloproteinases critical to egg hatching and louse development. Abametapir can inhibit hatching of both head and body louse[1][2].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Metabolic Enzyme/Protease >> MMP
In Vitro	Abametapir is capable of chelating heavy metal ions, including iron, copper, and zinc, and is therefore able to interact with a range of targets within the insect that require metal co-factors for function, including metalloproteinases[2].
References	[1]. Vernon Morrison Bowles, et al. Effect of a New Head Lice Treatment, Abametapir Lotion, 0.74%, on Louse Eggs: A Randomized, Double-Blind Study. Glob Pediatr Health. 2019; 6: 2333794X19831295. [2]. Vernon M. Bowles, et al. Ovicidal Efficacy of Abametapir Against Eggs of Human Head and Body Lice (Anoplura: Pediculidae). J Med Entomol. 2017 Jan; 54(1): 167-172.

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TOXIA6 Toxicon. (Pergamon Press Ltd., Headington Hill Hall, Oxford OX3 OBW, UK) V.1- 1962- Volume(issue)/page/year: 23,815,1985

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302-H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi: Irritant;
Risk Phrases	R36/37/38
Safety Phrases	S26-S36
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	DW1766000
HS Code	2933399090

HS Code	2933399090
Summary	2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%