- DC Chemicals Limited
- China
- Product Name: N-methyl Paroxetine
- Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: N-methylparoxetine
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Ms Wang
- Xi'an Reach Pharmaceutical Technology Co.,Ltd.
- China
- Product Name: N-Methyl Paroxetine
- Price: ￥Inquiry/1kg
- Purity: 96.0%
- Stocking Period: Inquiry
- Contact: Grace
- Henan Tianfu Chemical Co., Ltd.
- China
- Product Name: N-Methylparoxetine_
- Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
- Purity: 99.0%
- Stocking Period: Inquiry
- Contact: Anson
110429-36-2
110429-36-2 structure
- Name: N-Methylparoxetine
- Chemical Name: N-Methyl Paroxetine
- CAS Number: 110429-36-2
- Molecular Formula: C20H22FNO3
- Molecular Weight: 343.392
- Create Date: 2018-07-14 15:57:25
- Modify Date: 2024-01-02 16:24:20
-
N-methyl Paroxetine is a derivative of the selective serotonin reuptake inhibitor (SSRI) antidepressant paroxetine that inhibits [3H]paroxetine binding to rat cortical membranes. It inhibits serotonin (5-HT) uptake in rat brain synaptosomes and has been used as a precursor in the synthesis of paroxetine.
| Name | N-Methyl Paroxetine |
|---|---|
| Synonyms |
Piperidine, 3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-1-methyl-
Paroxetine Related Compound F 3-[(1,3-Benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-1-methylpiperidine Piperidine, 3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-1-methyl-, (3S,4R)- (3S,4R)-3-(1,3-benzodioxol-5-yloxymethyl)-4-(4-fluorophenyl)-1-methylpiperidine MFCD03788781 N-Methyl Paroxetine (3S,4R)-3-[(1,3-Benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-1-methylpiperidine Paroxetine Impurity 9 |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 443.7±45.0 °C at 760 mmHg |
| Melting Point | 111 °C |
| Molecular Formula | C20H22FNO3 |
| Molecular Weight | 343.392 |
| Flash Point | 222.1±28.7 °C |
| Exact Mass | 343.158386 |
| PSA | 30.93000 |
| LogP | 3.91 |
| Vapour Pressure | 0.0±1.1 mmHg at 25°C |
| Index of Refraction | 1.562 |
| Storage condition | Hygroscopic, -20°C Freezer, Under Inert Atmosphere |
| Symbol |
GHS06, GHS09 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H301-H410 |
| Precautionary Statements | P273-P301 + P310-P501 |
| Hazard Codes | T,N |
| Risk Phrases | 25-50/53 |
| Safety Phrases | 45-60-61 |
| RIDADR | UN 2811 6.1 / PGIII |
| Hazard Class | 6.1 |
|
~78%
110429-36-2 |
| Literature: Segura, Mireia; Roura, Lidia; De La Torre, Rafael; Joglar, Jesus Bioorganic Chemistry, 2003 , vol. 31, # 3 p. 248 - 258 |
|
~92%
110429-36-2 |
| Literature: Wei, Peng; Kaatz, Glenn W.; Kerns, Robert J. Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 12 p. 3093 - 3097 |
|
~%
110429-36-2 |
| Literature: Bioorganic Chemistry, , vol. 31, # 3 p. 248 - 258 |
|
~%
110429-36-2 |
| Literature: Synthetic Communications, , vol. 42, # 22 p. 3344 - 3360 |
|
~%
110429-36-2 |
| Literature: EP1286965 B1, ; Page 5 ; |
| Precursor 6 | |
|---|---|
| DownStream 2 | |
