53696-59-6
53696-59-6 structure
- Name: 8-Azido-ATP
- Chemical Name: 8-azidoadenosine 5'-triphosphate, sodium salt
- CAS Number: 53696-59-6
- Molecular Formula: C10H14N8NaO13P3
- Molecular Weight: 570.17500
- Catalog: Biochemical Nucleoside drugs Nucleoside intermediate
- Create Date: 2018-08-08 14:45:56
- Modify Date: 2024-01-09 12:07:34
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8-Azido-ATP, a photoreactable nucleotide analog, is useful for the identification of proteins, such as DNA-dependent RNA polymerase[1].
| Name | 8-azidoadenosine 5'-triphosphate, sodium salt |
|---|---|
| Synonyms |
Adenosine 5'-(tetrahydrogen triphosphate),8-azido
8-Azido-D-adenosine5'-triphosphatesodiumsalt 8-AZIDOADENOSINE-5'-O-TRIPHOSPHATE SODIUM SALT 8-N3-ATP SODIUM SALT |
| Description | 8-Azido-ATP, a photoreactable nucleotide analog, is useful for the identification of proteins, such as DNA-dependent RNA polymerase[1]. |
|---|---|
| Related Catalog | |
| In Vitro | 8-Azido-ATP can be used to identify the viral RNA polymerase on the basis of the ability of the analog to inhibit transcription activity associated with rotavirus particles on exposure to UV light[1]. 8-Azido-ATP (azido-ATP) decreases viral transcription in a dose-dependent manner[1]. 8-Azido-ATP blocks Kir6.2ΔC26 currents rather less potently than ATP, half-maximal inhibition (Ki) occurring at 2.8 ± 0.4 mM (n = 6) compared with 172 ± 7 mM for ATP (n = 6). The Hill coefficients were 0.9 ± 0.2 for 8-azido-ATP and 1.3 ± 0.1 for ATP[2]. |
| References |
| Molecular Formula | C10H14N8NaO13P3 |
|---|---|
| Molecular Weight | 570.17500 |
| Exact Mass | 569.97900 |
| PSA | 336.11000 |
| Hazard Codes | Xi |
|---|