Name | (2S)-2-(3-benzoylphenyl)-3,3,3-trideuteriopropanoic acid |
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Description | Ketoprofen-13C,d3 is the 13C- and deuterium labeled. Ketoprofen (RP-19583) is a non-steroidal antiinflammatory agent, acting as a potent inhibitor of COX, with IC50s of 2 nM and 26 nM for COX-1 and COX-2 in human blood monocytes, respectively[1]. |
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Related Catalog | |
In Vitro | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[85]. |
References |
Molecular Formula | C1513CH11D3O3 |
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Molecular Weight | 258.29 |
Exact Mass | 258.11600 |
PSA | 54.37000 |
LogP | 3.10570 |