487-24-1

487-24-1 structure

Name: 7-Hydroxy-4'-methoxyflavone
Chemical Name: 7-hydroxy-2-(4-methoxyphenyl)chromen-4-one
CAS Number: 487-24-1
Molecular Formula: C₁₆H₁₂O₄
Molecular Weight: 268.26
Catalog: Research Areas Inflammation/Immunology
Create Date: 2018-09-22 09:54:18
Modify Date: 2024-01-31 19:11:51
Pratol is a potent inhibitor of NF-κB. Pratol significantly reduces NO and prostaglandin PGE2 production without any cytotoxic in LPS-stimulated RAW 264.7 cells. Pratol reduces proinflammatory cytokines. Pratol can be used in study inflammatory diseases and cancer[1].

Name	7-hydroxy-2-(4-methoxyphenyl)chromen-4-one
Synonyms	Flavone,7-hydroxy-4'-methoxy 7-Hydroxy-4'-methoxyflavone EINECS 207-653-2 4'-Methoxy-7-hydroxyflavone

Description	Pratol is a potent inhibitor of NF-κB. Pratol significantly reduces NO and prostaglandin PGE2 production without any cytotoxic in LPS-stimulated RAW 264.7 cells. Pratol reduces proinflammatory cytokines. Pratol can be used in study inflammatory diseases and cancer[1].
Related Catalog	Research Areas >> Inflammation/Immunology
References	[1]. Chung, Y. C. , et al. Anti-inflammatory Effect of Pratol in LPS-stimulated RAW 264.7 Cells via NF-κB Signaling Pathways. Natural Product Communications, 13(5), 1934578X1801300.

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia, Italy) V.8-43 1953-88 For publisher information, see FRMCE8 Volume(issue)/page/year: 38,67,1983

Hazard Codes	Xi