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DC Chemicals Limited
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Dayang Chem (Hangzhou) Co., Ltd.
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59756-60-4

59756-60-4 structure

59756-60-4 structure

Name: Fluridone
Chemical Name: fluridone
CAS Number: 59756-60-4
Molecular Formula: C₁₉H₁₄F₃NO
Molecular Weight: 329.316
Catalog: Chemical pesticide herbicide Other herbicides
Create Date: 2018-05-12 08:00:00
Modify Date: 2024-01-02 16:04:31
Fluridone is an inhibitor of abscisic acid (ABA) biosynthesis. Fluridone suppresses the expression of AchnFAR and TF genes and reduces the formation of primary alcohols[1].

Name	fluridone
Synonyms	1-Methyl-3-phenyl-5-[3-(trifluoromethyl)phenyl]pyridin-4(1H)-one 1-Methyl-3-phenyl-5-[3-(trifluoromethyl)phenyl]-4(1H)-pyridinone 1-methyl-3-phenyl-5-(α,α,α-trifluoro-m-tolyl)-4-pyridone Fluridone Sonar 4(1H)-Pyridinone, 1-methyl-3-phenyl-5-[3-(trifluoromethyl)phenyl]- Fluridon Sonar X 1-methyl-3-phenyl-5-[3-(trifluoromethyl)phenyl]pyridin-4-one 1-Methyl-3-phenyl-5-(a,a,a-trifluoro-m-tolyl)-4-pyridone MFCD00078682 Pride EINECS 261-916-6 Brake 1-Methyl-3-phenyl-5-[3-(trifluormethyl)phenyl]pyridin-4(1H)-on

Description	Fluridone is an inhibitor of abscisic acid (ABA) biosynthesis. Fluridone suppresses the expression of AchnFAR and TF genes and reduces the formation of primary alcohols[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Wei X, et al. MYB41, MYB107, and MYC2 promote ABA-mediated primary fatty alcohol accumulation via activation of AchnFAR in wound suberization in kiwifruit. Hortic Res. 2020;7(1):86.

Density	1.3±0.1 g/cm3
Boiling Point	444.4±45.0 °C at 760 mmHg
Melting Point	154-155°C
Molecular Formula	C₁₉H₁₄F₃NO
Molecular Weight	329.316
Flash Point	222.6±28.7 °C
Exact Mass	329.102753
PSA	22.00000
LogP	3.70
Vapour Pressure	0.0±1.1 mmHg at 25°C
Index of Refraction	1.568
Storage condition	0-6°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UU7786500

CHEMICAL NAME :: 4(1H)-Pyridinone, 1-methyl-3-phenyl-5-(3-(trifluoromethyl)phenyl)-

CAS REGISTRY NUMBER :: 59756-60-4

BEILSTEIN REFERENCE NO. :: 1547990

LAST UPDATED :: 199710

DATA ITEMS CITED :: 11

MOLECULAR FORMULA :: C19-H14-F3-N-O

MOLECULAR WEIGHT :: 329.34

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >10 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,418,1991

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >2130 gm/m3/1H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85JFAN "Agrochemicals Handbook," with updates, Hartley, D., and H. Kidd, eds., Nottingham, Royal Soc. of Chemistry, 1983-86 Volume(issue)/page/year: A582,1985

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >10 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,418,1991

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: >500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,418,1991

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - cat

DOSE/DURATION :: >250 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,418,1991

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: >500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,418,1991

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - quail

DOSE/DURATION :: >2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,418,1991 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 34908 mg/kg/1Y-C

TOXIC EFFECTS :: Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis) Blood - pigmented or nucleated red blood cells Blood - changes in erythrocyte (RBC) count

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0545242

Symbol	GHS06, GHS09
Signal Word	Danger
Hazard Statements	H311-H411
Precautionary Statements	P273-P280-P312
Personal Protective Equipment	Eyeshields;Faceshields;Gloves
Hazard Codes	N:Dangerousfortheenvironment;
Risk Phrases	R51/53
Safety Phrases	S60-S36/37
RIDADR	UN 3077
RTECS	UU7786500
Packaging Group	III

59756-57-9 structure

59756-57-9

74-89-5 structure

74-89-5

~95%

59756-60-4 structure

59756-60-4

Literature: Eli Lilly and Company Patent: US4152136 A1, 1979 ;

59756-57-9 structure

59756-57-9

107-31-3 structure

107-31-3

~%

59756-60-4 structure

59756-60-4

Literature: US4235619 A1, ;

59756-57-9 structure

59756-57-9

60-29-7 structure

60-29-7

5815-08-7 structure

5815-08-7

74-89-5 structure

74-89-5

~%

Detail

Literature: US4152136 A1, ;