CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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QL3850000
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CHEMICAL NAME :
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1-Naphthol, 2,4-dinitro-
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CAS REGISTRY NUMBER :
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605-69-6
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BEILSTEIN REFERENCE NO. :
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2057462
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LAST UPDATED :
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199710
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DATA ITEMS CITED :
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12
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MOLECULAR FORMULA :
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C10-H6-N2-O5
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MOLECULAR WEIGHT :
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234.18
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WISWESSER LINE NOTATION :
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L66J BQ CNW ENW
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Administration onto the skin
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SPECIES OBSERVED :
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Human
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DOSE/DURATION :
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50 mg/kg
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TOXIC EFFECTS :
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Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Behavioral - wakefulness Gastrointestinal - nausea or vomiting
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Intravenous
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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180 mg/kg
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TOXIC EFFECTS :
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Details of toxic effects not reported other than lethal dose value
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TYPE OF TEST :
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LDLo - Lowest published lethal dose
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ROUTE OF EXPOSURE :
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Intravenous
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SPECIES OBSERVED :
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Mammal - dog
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DOSE/DURATION :
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13300 ug/kg
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TOXIC EFFECTS :
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Cardiac - other changes Lungs, Thorax, or Respiration - chronic pulmonary edema Nutritional and Gross Metabolic - body temperature increase
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TYPE OF TEST :
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LDLo - Lowest published lethal dose
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ROUTE OF EXPOSURE :
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Subcutaneous
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SPECIES OBSERVED :
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Rodent - guinea pig
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DOSE/DURATION :
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80 mg/kg
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TOXIC EFFECTS :
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Details of toxic effects not reported other than lethal dose value
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TYPE OF TEST :
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LDLo - Lowest published lethal dose
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ROUTE OF EXPOSURE :
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Intraperitoneal
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SPECIES OBSERVED :
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Bird - pigeon
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DOSE/DURATION :
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15 mg/kg
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TOXIC EFFECTS :
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Details of toxic effects not reported other than lethal dose value
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TYPE OF TEST :
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LDLo - Lowest published lethal dose
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ROUTE OF EXPOSURE :
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Intravenous
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SPECIES OBSERVED :
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Bird - pigeon
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DOSE/DURATION :
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15 mg/kg
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TOXIC EFFECTS :
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Lungs, Thorax, or Respiration - dyspnea Nutritional and Gross Metabolic - body temperature increase
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Intramuscular
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SPECIES OBSERVED :
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Bird - pigeon
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DOSE/DURATION :
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18500 ug/kg
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TOXIC EFFECTS :
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Nutritional and Gross Metabolic - body temperature increase
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TYPE OF TEST :
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LDLo - Lowest published lethal dose
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ROUTE OF EXPOSURE :
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Subcutaneous
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SPECIES OBSERVED :
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Amphibian - frog
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DOSE/DURATION :
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60 mg/kg
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TOXIC EFFECTS :
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Details of toxic effects not reported other than lethal dose value
MUTATION DATA
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TYPE OF TEST :
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Mutation in microorganisms
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TEST SYSTEM :
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Bacteria - Salmonella typhimurium
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DOSE/DURATION :
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50 ug/plate
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REFERENCE :
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GDIKAN Gifu Daigaku Igakubu Kiyo. Papers of the Gifu University School of Medicine. (Gifu Daigaku Igakubu, 40 Tsukasa-machi, Gifu 500, Japan) V.15- 1967- Volume(issue)/page/year: 29,278,1981
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