251908-92-6

251908-92-6 structure

Name: AM 1172
Chemical Name: 4-hydroxy-N-icosa-5,8,11,14-tetraenylbenzamide
CAS Number: 251908-92-6
Molecular Formula: C₂₇H₃₉NO₂
Molecular Weight: 409.604
Create Date: 2016-04-12 14:33:15
Modify Date: 2025-08-25 10:12:35
AM1172 is metabolically stable anandamide uptake inhibitor and FAAH inhibitor[1][2].

Name	4-hydroxy-N-icosa-5,8,11,14-tetraenylbenzamide
Synonyms	4-Hydroxy-N-[(5Z,8Z,11Z,14Z)-5,8,11,14-icosatetraen-1-yl]benzamide 4-Hydroxy-N-[(5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraen-1-yl]benzamide am1172 Benzamide, N-[(5Z,8Z,11Z,14Z)-5,8,11,14-eicosatetraen-1-yl]-4-hydroxy-

Description	AM1172 is metabolically stable anandamide uptake inhibitor and FAAH inhibitor[1][2].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> FAAH Research Areas >> Neurological Disease Signaling Pathways >> Neuronal Signaling >> FAAH
References	[1]. Fegley D, et al. Anandamide transport is independent of fatty-acid amide hydrolase activity and is blocked by the hydrolysis-resistant inhibitor AM1172. Proc Natl Acad Sci U S A. 2004 Jun 8;101(23):8756-61. [2]. Kaczocha M, et al. Anandamide uptake is consistent with rate-limited diffusion and is regulated by the degree of its hydrolysis by fatty acid amide hydrolase. J Biol Chem. 2006 Apr 7;281(14):9066-75.