- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: Protosappanin B
- Price:
- Purity: 98.0%
- Stocking Period: 10 Day
- Contact: Yang
- BioBioPha
- China
- Product Name: Protosappanin B
- Price: ￥Inquiry/5mg
- Purity: 96.0%
- Stocking Period: 10 Day
- Contact: Xueping-Zheng
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: Protosappanin B
- Price: ￥4480.0/5mg
- Purity: 98.0%
- Stocking Period: 1 Day
- Contact: Liu jia
- DC Chemicals Limited
- China
- Product Name: Protosappanin B
- Price: $280.0/20mg
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: (7S)-3,7,10,11-Tetrahydroxy-7,8-dihydro-6H-dibenzo[b,d]oxocin-7-methanol
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Ms Wang
102036-29-3
102036-29-3 structure
- Name: Protosappanin B
- Chemical Name: Protosappanin B
- CAS Number: 102036-29-3
- Molecular Formula: C16H16O6
- Molecular Weight: 304.29
- Catalog: Natural product Phenols
- Create Date: 2018-02-12 08:00:00
- Modify Date: 2024-01-02 18:49:10
-
Protosappanin B is a phenolic compound extracted from Lignum Sappan. Anti-cancer activity[1]. Protosappanin B induces apoptosis and causes G1 cell cycle arrest in human bladder cancer cells[2].
| Name | Protosappanin B |
|---|---|
| Synonyms |
(7S)-7-(Hydroxymethyl)-7,8-dihydro-6H-dibenzo[b,d]oxocine-3,7,10,11-tetrol
6H-Dibenz[b,d]oxocin-3,7,10,11-tetrol, 7,8-dihydro-7-(hydroxymethyl)-, (7S)- |
| Description | Protosappanin B is a phenolic compound extracted from Lignum Sappan. Anti-cancer activity[1]. Protosappanin B induces apoptosis and causes G1 cell cycle arrest in human bladder cancer cells[2]. |
|---|---|
| Related Catalog | |
| Target |
Apoptosis[2] |
| In Vitro | Protosappanin B (12.5, 25, 50, 100, 200 µg/mL, 48 hours) dose-dependently inhibits tumor cells, with IC50s of 21.32 µg/mL, 26.73 µg/mL, and 76.53 µg/mL for SW-480, HCT-116, and BTT cells, respectively[1]. Cell Viability Assay[1] Cell Line: CT-116, SW-480, and BTT Cells Concentration: 12.5, 25, 50, 100, 200 µg/mL Incubation Time: 48 hours Result: Dose-dependently inhibited tumor cells after 48 hours of treatment. |
| References |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 655.5±55.0 °C at 760 mmHg |
| Molecular Formula | C16H16O6 |
| Molecular Weight | 304.29 |
| Flash Point | 350.2±31.5 °C |
| Exact Mass | 304.094696 |
| PSA | 110.38000 |
| LogP | 1.13 |
| Vapour Pressure | 0.0±2.1 mmHg at 25°C |
| Index of Refraction | 1.700 |
| Storage condition | 2~8℃ |
| Hazard Codes | Xi |
|---|
|
~%
102036-29-3 |
| Literature: Chemical and Pharmaceutical Bulletin, , vol. 38, # 6 p. 1490 - 1494 |
|
~%
102036-29-3 |
| Literature: Chemical & Pharmaceutical Bulletin, , vol. 35, # 7 p. 3002 - 3005 |
| Precursor 1 | |
|---|---|
| DownStream 0 | |