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72458-85-6

72458-85-6 structure
72458-85-6 structure
  • Name: 11-Hydroxytephrosin
  • Chemical Name: 11-Hydroxytephrosin
  • CAS Number: 72458-85-6
  • Molecular Formula: C23H22O8
  • Molecular Weight: 426.42
  • Catalog: Natural product Flavonoids
  • Create Date: 2017-07-12 06:48:48
  • Modify Date: 2025-08-20 11:59:59
  • 11-Hydroxytephrosin is a potent inhibitor of NF-kappaB. NF-kappaB is known to play a crucial role in the regulation of genes controlling the immune system, apoptosis, tumor cell growth, and tissue differentiation[1].

Name 11-Hydroxytephrosin
Synonyms 3H-Bis(1)benzopyrano(3,4-b:6',5'-e)pyran-7(7aH)-one, 13,13a-dihydro-6,7a-dihydroxy-9,10-dimethoxy-3,3-dimethyl-, (7aR-cis)-
(7aR,13aR)-6,7a-Dihydroxy-9,10-dimethoxy-3,3-dimethyl-13,13a-dihydro-3H-chromeno[3,4-b]pyrano[2,3-h]chromen-7(7aH)-one
3H-[1]Benzopyrano[3,4-b]pyrano[2,3-h][1]benzopyran-7(7aH)-one, 13,13a-dihydro-6,7a-dihydroxy-9,10-dimethoxy-3,3-dimethyl-, (7aR,13aR)-
Description 11-Hydroxytephrosin is a potent inhibitor of NF-kappaB. NF-kappaB is known to play a crucial role in the regulation of genes controlling the immune system, apoptosis, tumor cell growth, and tissue differentiation[1].
Related Catalog
References

[1]. Dat NT, et al. Phenolic constituents of Amorpha fruticosa that inhibit NF-kappaB activation and related gene expression. J Nat Prod. 2008;71(10):1696-1700.

Density 1.4±0.1 g/cm3
Boiling Point 672.4±55.0 °C at 760 mmHg
Molecular Formula C23H22O8
Molecular Weight 426.42
Flash Point 236.8±25.0 °C
Exact Mass 426.131470
PSA 103.68000
LogP 5.52
Vapour Pressure 0.0±2.2 mmHg at 25°C
Index of Refraction 1.631
Hazard Codes Xi
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