19741-14-1

19741-14-1 structure

Name: 4-Amino-4-deoxy-10-methylpteroic acid
Chemical Name: 4-[(2,4-diaminopteridin-6-yl)methyl-methylamino]benzoic acid
CAS Number: 19741-14-1
Molecular Formula: C₁₅H₁₅N₇O₂
Molecular Weight: 325.325
Catalog: analytical chemistry Standard Pharmacopoeia Standards and Magazine Standards
Create Date: 2019-01-12 18:50:38
Modify Date: 2024-01-02 14:01:11
Methotrexate metabolite (DAMPA), the active metabolite of Methotrexate. Methotrexate is a folic acid antagonist that is widely used as an immunosuppressant and chemotherapeutic agent[1].

Name	4-[(2,4-diaminopteridin-6-yl)methyl-methylamino]benzoic acid
Synonyms	Methotrexate impurity E 4-(((2,4-Diaminopteridin-6-yl)methyl)(methyl)amino)benzoic acid S1584_Selleck 4-{[(2,4-Diaminopteridin-6-yl)methyl](methyl)amino}benzoic acid Benzoic acid, 4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]- 4-{[(2,4-Diamino-6-pteridinyl)methyl](methyl)amino}benzoic acid Deoxyaminopteroic acid DAMPA 4-{[(2,4-Diaminopteridin-6-yl)methyl]methylamino}benzoic acid 4-Amino-4-deoxy-10-methylpteroic acid Methotrexate Impurity 5

Description	Methotrexate metabolite (DAMPA), the active metabolite of Methotrexate. Methotrexate is a folic acid antagonist that is widely used as an immunosuppressant and chemotherapeutic agent[1].
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> Antifolate Research Areas >> Inflammation/Immunology
References	[1]. Schofield RC, et al. Development and validation of a turbulent flow chromatography and tandem mass spectrometry method for the quantitation of methotrexate and its metabolites 7-hydroxy methotrexate and DAMPA in serum. J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Oct 1;1002:169-75.

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%