Name | 3-Methylcyclopentadecanone |
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Synonyms |
EINECS 208-795-8
MFCD00211114 FEMA 3434 Musk Cyclopentadecanone, 3-methyl- 3-Methylcyclopentadecanone Muskone DL-MUSCONE dl-Muscone or 3-Methylcyclopentadecanone Musk Ketone moschusketone MUSCONE MUSCONE II |
Description | Muscone is the main active monomer of traditional Chinese medicine musk. Muscone inhibits NF-κB and NLRP3 inflammasome activation. Muscone remarkably decreases the levels of inflammatory cytokines (IL-1β, TNF-α and IL-6), and ultimately improves cardiac function and survival rate[1]. |
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Related Catalog | |
Target |
NF-κB NLRP3 TNF-α IL-1β IL-6 |
In Vitro | Muscone significantly downregulates the levels of LPS-induced inflammatory cytokines and inhibits NF-κB and NLRP3 inflammasome activation in Bone marrow-derived macrophages (BMDMs). Muscone serves as a promising and effective drug for post-myocardial infarction (MI) treatment[1]. |
References |
Density | 0.8±0.1 g/cm3 |
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Boiling Point | 329.5±10.0 °C at 760 mmHg |
Melting Point | 33ºC |
Molecular Formula | C16H30O |
Molecular Weight | 238.409 |
Flash Point | 145.3±11.3 °C |
Exact Mass | 238.229660 |
PSA | 17.07000 |
LogP | 6.33 |
Vapour Pressure | 0.0±0.7 mmHg at 25°C |
Index of Refraction | 1.437 |
Storage condition | -20°C |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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Safety Phrases | 26-36 |
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WGK Germany | 2 |
RTECS | MH7875000 |
HS Code | 2914700090 |
HS Code | 2914700090 |
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Summary | HS: 2914700090 halogenated, sulphonated, nitrated or nitrosated derivatives of ketones and quinones, whether or not with other oxygen function Tax rebate rate:9.0% Supervision conditions:none VAT:17.0% MFN tariff:5.5% General tariff:30.0% |