Muscone
Muscone structure
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Common Name | Muscone | ||
|---|---|---|---|---|
| CAS Number | 541-91-3 | Molecular Weight | 238.409 | |
| Density | 0.8±0.1 g/cm3 | Boiling Point | 329.5±10.0 °C at 760 mmHg | |
| Molecular Formula | C16H30O | Melting Point | 33ºC | |
| MSDS | N/A | Flash Point | 145.3±11.3 °C | |
Use of MusconeMuscone is the main active monomer of traditional Chinese medicine musk. Muscone inhibits NF-κB and NLRP3 inflammasome activation. Muscone remarkably decreases the levels of inflammatory cytokines (IL-1β, TNF-α and IL-6), and ultimately improves cardiac function and survival rate[1]. |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | 3-Methylcyclopentadecanone |
|---|---|
| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | Muscone is the main active monomer of traditional Chinese medicine musk. Muscone inhibits NF-κB and NLRP3 inflammasome activation. Muscone remarkably decreases the levels of inflammatory cytokines (IL-1β, TNF-α and IL-6), and ultimately improves cardiac function and survival rate[1]. |
|---|---|
| Related Catalog | |
| Target |
NF-κB NLRP3 TNF-α IL-1β IL-6 |
| In Vitro | Muscone significantly downregulates the levels of LPS-induced inflammatory cytokines and inhibits NF-κB and NLRP3 inflammasome activation in Bone marrow-derived macrophages (BMDMs). Muscone serves as a promising and effective drug for post-myocardial infarction (MI) treatment[1]. |
| References |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 0.8±0.1 g/cm3 |
|---|---|
| Boiling Point | 329.5±10.0 °C at 760 mmHg |
| Melting Point | 33ºC |
| Molecular Formula | C16H30O |
| Molecular Weight | 238.409 |
| Flash Point | 145.3±11.3 °C |
| Exact Mass | 238.229660 |
| PSA | 17.07000 |
| LogP | 6.33 |
| Vapour Pressure | 0.0±0.7 mmHg at 25°C |
| Index of Refraction | 1.437 |
| InChIKey | ALHUZKCOMYUFRB-UHFFFAOYSA-N |
| SMILES | CC1CCCCCCCCCCCCC(=O)C1 |
| Storage condition | -20°C |
This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.
This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Safety Phrases | 26-36 |
|---|---|
| WGK Germany | 2 |
| RTECS | MH7875000 |
| HS Code | 2914700090 |
This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.
| HS Code | 2914700090 |
|---|---|
| Summary | HS: 2914700090 halogenated, sulphonated, nitrated or nitrosated derivatives of ketones and quinones, whether or not with other oxygen function Tax rebate rate:9.0% Supervision conditions:none VAT:17.0% MFN tariff:5.5% General tariff:30.0% |
This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| EINECS 208-795-8 |
| MFCD00211114 |
| FEMA 3434 |
| Musk |
| 3-Methylcyclopentadecanone |
| Muskone |
| DL-MUSCONE |
| dl-Muscone or 3-Methylcyclopentadecanone |
| Musk Ketone |
| moschusketone |
| MUSCONE |
| MUSCONE II |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What are the uses of 3-Methylcyclopentadecanone? |
| A: Main uses of 3-Methylcyclopentadecanone: Muscone is the main active monomer of traditional Chinese medicine musk. Muscone inhibits NF-κB and NLRP3 inflammasome activation. Muscone remarkably decreases the levels of inflammatory cytokines (IL-1β, TNF-α and IL-6), and ultimately improves cardiac function and survival rate[1]. |
| Q: What is the boiling point of 3-Methylcyclopentadecanone? |
| A: Boiling point of 3-Methylcyclopentadecanone is 329.5±10.0 °C at 760 mmHg. |
| Q: What is the SMILES notation of 3-Methylcyclopentadecanone? |
| A: SMILES notation of 3-Methylcyclopentadecanone is CC1CCCCCCCCCCCCC(=O)C1. |
| Q: What is the English name of 3-Methylcyclopentadecanone? |
| A: The English name of 3-Methylcyclopentadecanone is 3-Methylcyclopentadecanone. |
| Q: What is the polar surface area (PSA) of 3-Methylcyclopentadecanone? |
| A: Polar surface area (PSA) of 3-Methylcyclopentadecanone is 17.07000. |
| Q: What is the melting point of 3-Methylcyclopentadecanone? |
| A: Melting point of 3-Methylcyclopentadecanone is 33ºC. |
| Q: What is the CAS number of 3-Methylcyclopentadecanone? |
| A: CAS number of 3-Methylcyclopentadecanone is 541-91-3. |
| Q: What is the molecular weight of 3-Methylcyclopentadecanone? |
| A: Molecular weight of 3-Methylcyclopentadecanone is 238.409. |
| Q: What are the storage conditions for 3-Methylcyclopentadecanone? |
| A: Storage conditions for 3-Methylcyclopentadecanone: -20°C. |
| Q: What is the LogP of 3-Methylcyclopentadecanone? |
| A: LogP of 3-Methylcyclopentadecanone is 6.33. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| BioBioPha |