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464-92-6

464-92-6 structure
464-92-6 structure
  • Name: Asiatic acid
  • Chemical Name: asiatic acid
  • CAS Number: 464-92-6
  • Molecular Formula: C30H48O5
  • Molecular Weight: 488.699
  • Catalog: API Special medicine Dermatology medication
  • Create Date: 2018-07-15 21:37:52
  • Modify Date: 2026-07-01 11:26:01
  • Asiatic acid, a pentacyclic triterpene found in Centella asiatica, induces apoptosis in melanoma cells. Asiatic acid can be used to treat skin cancer[1]. Asiatic acid also has anti-inflammatory activities[2].

Name asiatic acid
Synonyms 2alpha,3beta,23-Trihydroxy-12-ursen-28-oic Acid
Asiatic Acid >
Centellaasiatica(L.)Urb
(1S,2R,4aS,6aS,6bR,8,9R,10R,11R,12,12bR,14bS)-10,11-dihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-1,3,4,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-octadecahydropicene-4a(2H)-cboxylic acid
MFCD00238541
2α,3β,23-Trihydroxyurs-12-ene-28-oic acid
Asiatic acid //BP
Dammarolic acid
EINECS 482-720-9
Gotu kola extract,Centella asiatica
ASIATICA ACID
2α,3β,23-Trihydroxyurs-12-en-28-oicacid
10,11-dihydroxy-9-(hydroxyMethyl)-1,2,6a,6b,9,12a-hexaMethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-cboxylic acid
2alpha,23-Dihydroxyursolic Acid
Snow oxalic acid
Asiatic acid (6CI)
Asiatic acid (AA)
DaMMolic acid
Asiantic acid
URS-12-EN-28-OIC ACID, 2,3,23-TRIHYDROXY-, (2A,3B,4A)
ASIATIC ACID(P)
(1S,2R,4aS,6,6aS,6bR,8,9R,10R,11R,12,14bS)-10,11-dihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-cboxylic acid
UNII-9PA5A687X5
2α,23-Dihydroxyursolic acid
ASIATIC ACID
Asiatic acid-RM
2,3,23-TRIHYDROXY-12-URSEN-28-OIC ACID
(2α,3β)-2,3,23-Trihydroxyurs-12-en-28-oic acid
Asiaticacid
Asiatic acid (1S,2R,4aS,6,6aS,6bR,8,9S,10S,11R,12aS,14bR)-10,11-Dihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-cboxylic acid
(4R)-2α,3β,23-Trihydroxyurs-12-en-28-oic acid
ASIATICACID:URS-12-EN-28-OICACID, 2,3,23-TRIHYDROXY-, (2A,3B,4A)
Asiatic Acid (Dammolic acid, Asiantic acid)
Urs-12-en-28-oic acid, 2,3,23-trihydroxy-, (2.alpha.,3.beta.,4.alpha.)
Urs-12-en-28-oic acid, 2,3,23-trihydroxy-, (2α,3β,4α)
(1s,2r,4as,6,6as,6br,8,9s,10s,11r,12as,14br)-10,11-dihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1h-picene-4a-cboxylic acid
Description Asiatic acid, a pentacyclic triterpene found in Centella asiatica, induces apoptosis in melanoma cells. Asiatic acid can be used to treat skin cancer[1]. Asiatic acid also has anti-inflammatory activities[2].
Related Catalog
References

[1]. Park BC, et al. Asiatic acid induces apoptosis in SK-MEL-2 human melanoma cells. Cancer Lett. 2005 Jan 31;218(1):81-90.

[2]. Huang SS, et al. Antinociceptive activities and the mechanisms of anti-inflammation of asiatic Acid in mice. Evid Based Complement Alternat Med. 2011;2011:895857.

Density 1.2±0.1 g/cm3
Boiling Point 609.4±55.0 °C at 760 mmHg
Melting Point 325-330 °C(lit.)
Molecular Formula C30H48O5
Molecular Weight 488.699
Flash Point 336.4±28.0 °C
Exact Mass 488.350189
PSA 97.99000
LogP 6.46
Vapour Pressure 0.0±4.0 mmHg at 25°C
Index of Refraction 1.579
Storage condition 2-8°C
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi: Irritant;
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2918199090

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464-92-6 structure

464-92-6

Literature: SHANGHAI INSTITUTE OF PHARMACEUTICAL INDUSTRY (SIPI) Patent: WO2009/89365 A2, 2009 ; Location in patent: Page/Page column 6-7 ;
Precursor  1

DownStream  0

HS Code 2918199090
Summary 2918199090 other carboxylic acids with alcohol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%
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