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  • BioBioPha
  • China
  • Product Name: Peiminine
  • Price: ¥Inquiry/5mg
  • Purity: 98.0%
  • Stocking Period: 10 Day
  • Contact: Xueping-Zheng


18059-10-4

18059-10-4 structure
18059-10-4 structure
  • Name: Peiminine
  • Chemical Name: Peiminine
  • CAS Number: 18059-10-4
  • Molecular Formula: C27H43NO3
  • Molecular Weight: 429.635
  • Catalog: Biochemical Chinese herbal medicine ingredients
  • Create Date: 2018-08-31 22:52:32
  • Modify Date: 2024-01-02 11:03:52
  • Peiminine(Verticinone; Raddeanine) is a natural compound with anti-inflammatory activity.IC50 value:Target:Peiminine and DXS significantly reduced alveolar inflammation and pulmonary interstitial inflammation in rats with bleomycin-induced lung injury. peiminine inhibits lung inflammation and pulmonary fibrosis in a rat model of bleomycin-induced lung injury, by reducing circulating IFN-γ levels and inhibiting signal transduction pathways involving TGF-β, CTGF, ERK1/2, NF-κB and FasL.

Name Peiminine
Synonyms MFCD00210542
(3β)-3,20-Dihydroxycevan-6-one
Osnovanine
Raddeamine
(3β,5α)-3,20-Dihydroxycevan-6-one
Cevan-6-one, 3,20-dihydroxy-, (3β,5α)-
Sipeimine
3beta,20-Dihydroxy-5alpha-cevan-6-one
3β,20-Dihydroxy-5α-cevan-6-one
(3b)-3,20-Dihydroxycevan-6-one
RADDEANINE
Cevan-6-one, 3,20-dihydroxy-, (3β)-
cevan-6-one, 3,20-dihydroxy-, (3b)-
PEINININE
Fritillarine
Verticinone
Description Peiminine(Verticinone; Raddeanine) is a natural compound with anti-inflammatory activity.IC50 value:Target:Peiminine and DXS significantly reduced alveolar inflammation and pulmonary interstitial inflammation in rats with bleomycin-induced lung injury. peiminine inhibits lung inflammation and pulmonary fibrosis in a rat model of bleomycin-induced lung injury, by reducing circulating IFN-γ levels and inhibiting signal transduction pathways involving TGF-β, CTGF, ERK1/2, NF-κB and FasL.
Related Catalog
References

[1]. Guo H, et al. Peiminine ameliorates bleomycin-induced acute lung injury in rats. Mol Med Rep. 2013 Apr;7(4):1103-10.

Density 1.2±0.1 g/cm3
Boiling Point 567.1±50.0 °C at 760 mmHg
Melting Point 212-213ºC
Molecular Formula C27H43NO3
Molecular Weight 429.635
Flash Point 296.8±30.1 °C
Exact Mass 429.324280
PSA 60.77000
LogP 3.90
Vapour Pressure 0.0±3.5 mmHg at 25°C
Index of Refraction 1.585
Hazard Codes Xi

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18059-10-4 structure

18059-10-4

Literature: Heterocycles, , vol. 15, # 2 p. 791 - 796
Precursor  1

DownStream  0