Name | Peiminine |
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Synonyms |
MFCD00210542
(3β)-3,20-Dihydroxycevan-6-one Osnovanine Raddeamine (3β,5α)-3,20-Dihydroxycevan-6-one Cevan-6-one, 3,20-dihydroxy-, (3β,5α)- Sipeimine 3beta,20-Dihydroxy-5alpha-cevan-6-one 3β,20-Dihydroxy-5α-cevan-6-one (3b)-3,20-Dihydroxycevan-6-one RADDEANINE Cevan-6-one, 3,20-dihydroxy-, (3β)- cevan-6-one, 3,20-dihydroxy-, (3b)- PEINININE Fritillarine Verticinone |
Description | Peiminine(Verticinone; Raddeanine) is a natural compound with anti-inflammatory activity.IC50 value:Target:Peiminine and DXS significantly reduced alveolar inflammation and pulmonary interstitial inflammation in rats with bleomycin-induced lung injury. peiminine inhibits lung inflammation and pulmonary fibrosis in a rat model of bleomycin-induced lung injury, by reducing circulating IFN-γ levels and inhibiting signal transduction pathways involving TGF-β, CTGF, ERK1/2, NF-κB and FasL. |
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Related Catalog | |
References |
Density | 1.2±0.1 g/cm3 |
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Boiling Point | 567.1±50.0 °C at 760 mmHg |
Melting Point | 212-213ºC |
Molecular Formula | C27H43NO3 |
Molecular Weight | 429.635 |
Flash Point | 296.8±30.1 °C |
Exact Mass | 429.324280 |
PSA | 60.77000 |
LogP | 3.90 |
Vapour Pressure | 0.0±3.5 mmHg at 25°C |
Index of Refraction | 1.585 |
Hazard Codes | Xi |
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~% 18059-10-4 |
Literature: Heterocycles, , vol. 15, # 2 p. 791 - 796 |
Precursor 1 | |
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DownStream 0 |