120011-70-3
120011-70-3 structure
- Name: Donepezil Hydrochloride
- Chemical Name: donepezil hydrochloride
- CAS Number: 120011-70-3
- Molecular Formula: C24H30ClNO3
- Molecular Weight: 415.953
- Catalog: Biochemical Inhibitor Neuronal Signaling AChR inhibitor
- Create Date: 2018-07-19 19:38:46
- Modify Date: 2026-07-03 13:39:51
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Donepezil Hcl(E-2020) is a noncompetitive acetylcholinesterase inhibitor, which can readily cross the blood brain barrier and increases the concentration of cortical acetylcholine. IC50 Value:Target: AChEIt is known that Donepezil Hydrochloride is a useful tool in the study of Alzheimer's disease. Studies indicate that Donepezil Hydrochloride protects the brain against diisopropylfluorophosphate-induced effects. Studies indicate that Donepezil Hydrochloride selectively inhibits acetylcholinesterase, whereas it has little effect on butyrylcholinesterase. Alternate studies suggest that Donepezil Hydrochloride increases the concentration of extracellular acetylcholine in the cerebral cortex and hippocampus of rats.
| Name | donepezil hydrochloride |
|---|---|
| Synonyms |
2,3-dihydro-5,6-dimethoxy-2-((1-(phenylmethyl)-4-piperidinyl)methyl)-1h-inden-1-onhydrochloride
MFCD00881312 2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one hydrochloride (1:1) 2-((1-Benzylpiperidin-4-yl)Methyl)-5 2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxyindan-1-one hydrochloride Donezil Hydrochloride ForM Ⅰ 2-((1-Benzylpiperidin-4-yl)Methyl)-5,6-diMethoxy-2,3-dihydro-1H-inden-1-one hydrochloride Donezi Donezil-d7 Hydrochloride DonezilHydrochloride> 2,3-Dihydro-5,6-diMethoxy-2-[[1-(phenylMethyl)-4-piperidinyl]Methyl] Donezil HCl (type III) 2,3-dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-1H-inden-1-one,hydrochloride (1:1) DONEZIL HYDROCHLORIDE ict, E-2020 Donepezil HCl 2,3-Dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]-1H-inden-1-one Donepezil hydrochloride Donezil hydrochloride in methanol Donezam hydrochloride 2-((1-Benzylpiperidin-4-yl)methyl)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one hydrochloride 2-[(1-Benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydro-1H-inden-1-onhydrochlorid Donezil HydrochlorideQ: What is Donezil Hydrochloride Q: What is the CAS Number of Donezil Hydrochloride Q: What is the storage condition of Donezil Hydrochloride Q: What e the applications of Donezil Hydrochloride donpezil hydrochloride onezilhydrochloride DONEZIL HYDROCHLORIDE , NON-STERILE DRUG SUBSTANCE HYDROGEN DONEZIL CHLORIDE DONEZIL HCL IP Donezil hydrochloride (Y0002160) 2-[(1-Benzyl-4-piperidinyl)methyl]-5,6-dimethoxy-1-indanone hydrochloride (1:1) Donezil hydrochloride (III) E-2020 2-[(1-Benzyl-4-piperidinyl)methyl]-5,6-dimethoxy-1-indanone hydrochloride Chemical Donezil Hydrochloride 1H-inden-1-one, 2,3-dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-, hydrochloride Donezil Hydrochloride (±)-2-[(1-Benzyl-4-piperidyl)methyl]-5,6-dimethoxy-1-indanone hydrochloride Donezil HCl (E2020) Donepezil Donezil Hydrochloride RS Donezil Hydrochloride //BP bnag 3-dihydro-1H-inden-1-one hydrochloride Donezil Hydrochloride 1.0 mg/ml in Methanol (as free base) 2-(1-Benzyl-4-piperidylmethyl)-5,6-dimethoxy-1-indanone Hydrochloride Donezil Hydrochloride, 10 mM in DMSO 5,6-Dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-2,3-dihydro-1H-inden-1-one Hydrochloride 1H-Inden-1-one, 2,3-dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-, hydrochloride (1:1) Donezil HCl - Bio-X Donezil HCL (under development) e2020(phmaceutical) Donezil hydrochloride, Acetylcholinesterase inhibitor DOPEZIL HCL Donezil ict) Donezil hydrochloride a noncompetitive acetylcholinesterase inhibitor, which can readily cross the blood brain brier and increases the concentration of cortical acetylcholine 1h-inden-1-one,2,3-dihydro-5,6-dimethoxy-2-((1-(phenylmethyl)-4-piperidinyl)me 6-diMethoxy-2 2,3-Dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-1H-inden-1-one hydrochloride Donezil hydrochloride 2,3-Dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-1H-inden-1-one hydrochloride Donezil HCI 1-Benzyl-4-[(5,6-dimethoxy-1-indanon-2-yl)methyl]piperidine Hydrochloride 2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one hydrochloride DONEZIL HCL Donezil HCl and intermediates Donezil and its intermediates 2-[(1-Benzylpiperidin-4-yl)methyl]-5,6-dimethoxyindan-1-one hydrochloride (1:1) |
| Description | Donepezil Hcl(E-2020) is a noncompetitive acetylcholinesterase inhibitor, which can readily cross the blood brain barrier and increases the concentration of cortical acetylcholine. IC50 Value:Target: AChEIt is known that Donepezil Hydrochloride is a useful tool in the study of Alzheimer's disease. Studies indicate that Donepezil Hydrochloride protects the brain against diisopropylfluorophosphate-induced effects. Studies indicate that Donepezil Hydrochloride selectively inhibits acetylcholinesterase, whereas it has little effect on butyrylcholinesterase. Alternate studies suggest that Donepezil Hydrochloride increases the concentration of extracellular acetylcholine in the cerebral cortex and hippocampus of rats. |
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| Related Catalog | |
| References |
| Boiling Point | 527.9ºC at 760 mmHg |
|---|---|
| Melting Point | 220-222ºC |
| Molecular Formula | C24H30ClNO3 |
| Molecular Weight | 415.953 |
| Flash Point | 273.1ºC |
| Exact Mass | 415.191437 |
| PSA | 38.77000 |
| LogP | 5.10100 |
| Vapour Pressure | 3.11E-11mmHg at 25°C |
| Storage condition | -20°C Freezer |
| Hazard Codes | Xi: Irritant; |
|---|---|
| Risk Phrases | R36/37/38 |
| Safety Phrases | S26-S36 |
| RIDADR | UN 2811 |
| HS Code | 2933399090 |
| HS Code | 2933399090 |
|---|---|
| Summary | 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |