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1156-78-1

1156-78-1 structure
1156-78-1 structure
  • Name: 2',4',5,7-Tetrahydroxyisoflavone
  • Chemical Name: 2'-hydroxygenistein
  • CAS Number: 1156-78-1
  • Molecular Formula: C15H10O6
  • Molecular Weight: 286.24
  • Catalog: Natural product Flavonoids
  • Create Date: 2018-06-06 23:40:31
  • Modify Date: 2024-01-03 12:01:10
  • 2′-Hydroxygenistein is a natural product that can be isolated from Crotalaria pallida and C. assamica. 2′-Hydroxygenistein shows anti-inflammatory activity. 2′-Hydroxygenistein shows significant concentration-dependent inhibitory effects on the release of β-glucuronidase and lysozyme from rat neutrophils, with IC50 values of 5.9 ± 1.4 and 9.7 ± 3.5 μM, respectively[1].

Name 2'-hydroxygenistein
Synonyms 3-(2,4-dihydroxyphenyl)-5,7-dihydroxychromen-4-one
2',4',5,7-Tetrahydroxyisoflavone
Isoflavone, 2',4',5,7-tetrahydroxy-
2'-HYDROXYGENISTEIN
4H-1-Benzopyran-4-one, 3-(2,4-dihydroxyphenyl)-5,7-dihydroxy-
5,7,2',4'-Tetrahydroxy-isoflavone
3-(2,4-Dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one
MFCD00075967
Description 2′-Hydroxygenistein is a natural product that can be isolated from Crotalaria pallida and C. assamica. 2′-Hydroxygenistein shows anti-inflammatory activity. 2′-Hydroxygenistein shows significant concentration-dependent inhibitory effects on the release of β-glucuronidase and lysozyme from rat neutrophils, with IC50 values of 5.9 ± 1.4 and 9.7 ± 3.5 μM, respectively[1].
Related Catalog
References

[1]. Ko HH, Weng JR, Tsao LT, Yen MH, Wang JP, Lin CN. Anti-inflammatory flavonoids and pterocarpanoid from Crotalaria pallida and C. assamica. Bioorg Med Chem Lett. 2004 Feb 23;14(4):1011-4.  

Density 1.7±0.1 g/cm3
Boiling Point 619.1±55.0 °C at 760 mmHg
Molecular Formula C15H10O6
Molecular Weight 286.24
Flash Point 240.7±25.0 °C
Exact Mass 286.047729
PSA 111.13000
LogP 2.99
Vapour Pressure 0.0±1.9 mmHg at 25°C
Index of Refraction 1.768
Hazard Codes Xi
HS Code 2914501900
HS Code 2914501900
Summary 2914501900 other ketone-phenols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%