38231-86-6

38231-86-6 structure

Name: Valienamine
Chemical Name: (+)-Valienamine Hydrochloride
CAS Number: 38231-86-6
Molecular Formula: C₇H₁₃NO₄
Molecular Weight: 175.182
Catalog: API Antibiotics Other antibiotics
Create Date: 2018-02-21 08:00:00
Modify Date: 2024-01-05 13:30:08
Valienamine is the alpha-glucosidase inhibitor. Valienamine is the key functional component of many natural glycosidase inhibitors including the crop protectant validamycin A and the antidiabetic agent acarbose[1].

Name	(+)-Valienamine Hydrochloride
Synonyms	(1S,2S,3R,6S)-6-amino-4-(hydroxymethyl)cyclohex-4-ene-1,2,3-triol Valienamine (1S,2S,3R,6S)-6-Amino-4-(hydroxymethyl)-4-cyclohexene-1,2,3-triol MFCD07357238 4-Cyclohexene-1,2,3-triol, 6-amino-4-(hydroxymethyl)-, (1S,2S,3R,6S)-

Description	Valienamine is the alpha-glucosidase inhibitor. Valienamine is the key functional component of many natural glycosidase inhibitors including the crop protectant validamycin A and the antidiabetic agent acarbose[1].
Related Catalog	Research Areas >> Metabolic Disease
Target	alpha-glucosidase[1]
References	[1]. Degwert U, et al. Studies on the biosynthesis of the alpha-glucosidase inhibitor acarbose: valienamine, a m-C7N unit not derived from the shikimate pathway. J Antibiot (Tokyo). 1987;40(6):855-861. [2]. Cui L, et al. A Validamycin Shunt Pathway for Valienamine Synthesis in Engineered Streptomyces hygroscopicus 5008. ACS Synth Biol. 2020;9(2):294-303.

Density	1.5±0.1 g/cm3
Boiling Point	377.3±42.0 °C at 760 mmHg
Molecular Formula	C₇H₁₃NO₄
Molecular Weight	175.182
Flash Point	182.0±27.9 °C
Exact Mass	175.084457
PSA	106.94000
LogP	-1.60
Vapour Pressure	0.0±1.9 mmHg at 25°C
Index of Refraction	1.649
Storage condition	Hygroscopic, Store under Inert atmosphere Refrigerator

Hazard Codes	Xi
HS Code	2922199090

HS Code	2922199090
Summary	2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%