Valienamine

Modify Date: 2024-01-05 13:30:08

Valienamine Structure
Valienamine structure
Common Name Valienamine
CAS Number 38231-86-6 Molecular Weight 175.182
Density 1.5±0.1 g/cm3 Boiling Point 377.3±42.0 °C at 760 mmHg
Molecular Formula C7H13NO4 Melting Point N/A
MSDS N/A Flash Point 182.0±27.9 °C

 Use of Valienamine


Valienamine is the alpha-glucosidase inhibitor. Valienamine is the key functional component of many natural glycosidase inhibitors including the crop protectant validamycin A and the antidiabetic agent acarbose[1].

 Names

Name (+)-Valienamine Hydrochloride
Synonym More Synonyms

 Valienamine Biological Activity

Description Valienamine is the alpha-glucosidase inhibitor. Valienamine is the key functional component of many natural glycosidase inhibitors including the crop protectant validamycin A and the antidiabetic agent acarbose[1].
Related Catalog
Target

alpha-glucosidase[1]

References

[1]. Degwert U, et al. Studies on the biosynthesis of the alpha-glucosidase inhibitor acarbose: valienamine, a m-C7N unit not derived from the shikimate pathway. J Antibiot (Tokyo). 1987;40(6):855-861.

[2]. Cui L, et al. A Validamycin Shunt Pathway for Valienamine Synthesis in Engineered Streptomyces hygroscopicus 5008. ACS Synth Biol. 2020;9(2):294-303.

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 377.3±42.0 °C at 760 mmHg
Molecular Formula C7H13NO4
Molecular Weight 175.182
Flash Point 182.0±27.9 °C
Exact Mass 175.084457
PSA 106.94000
LogP -1.60
Vapour Pressure 0.0±1.9 mmHg at 25°C
Index of Refraction 1.649
Storage condition Hygroscopic, Store under Inert atmosphere Refrigerator

 Safety Information

Hazard Codes Xi
HS Code 2922199090

 Synthetic Route

 Customs

HS Code 2922199090
Summary 2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Synonyms

(1S,2S,3R,6S)-6-amino-4-(hydroxymethyl)cyclohex-4-ene-1,2,3-triol
Valienamine
(1S,2S,3R,6S)-6-Amino-4-(hydroxymethyl)-4-cyclohexene-1,2,3-triol
MFCD07357238
4-Cyclohexene-1,2,3-triol, 6-amino-4-(hydroxymethyl)-, (1S,2S,3R,6S)-
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