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321-14-2

321-14-2 structure
321-14-2 structure

Name 5-chlorosalicylic acid
Synonyms 5-Chlorosalicyclic acid
5-chloro-2-hydroxy-benzoic acid
Benzoic acid, 5-chloro-2-hydroxy-
5-chlorosalicylic acid
EINECS 206-283-9
Salicylic acid,5-chloro
2-Hydroxy-5-chlorobenzoic acid
tert-butyl carbazate
5-Chloro-2-hydroxybenzoic acid
MFCD00002457
5 CSA
Benzoic acid,5-chloro-2-hydroxy
5-chloro-salicylic acid
Density 1.5±0.1 g/cm3
Boiling Point 320.5±27.0 °C at 760 mmHg
Melting Point 171-172 °C(lit.)
Molecular Formula C7H5ClO3
Molecular Weight 172.566
Flash Point 147.6±23.7 °C
Exact Mass 171.992722
PSA 57.53000
LogP 3.42
Vapour Pressure 0.0±0.7 mmHg at 25°C
Index of Refraction 1.630
Water Solubility 1 g/L (20 ºC)

CHEMICAL IDENTIFICATION

RTECS NUMBER :
VO2080000
CHEMICAL NAME :
Salicylic acid, 5-chloro-
CAS REGISTRY NUMBER :
321-14-2
BEILSTEIN REFERENCE NO. :
2046665
LAST UPDATED :
199709
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C7-H5-Cl-O3
MOLECULAR WEIGHT :
172.57
WISWESSER LINE NOTATION :
QVR BQ EG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
250 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PHMGBN Pharmacology: International Journal of Experimental and Clinical Pharmacology. (S. Karger AG, Postfach CH-4009 Basel, Switzerland) V.1- 1968- Volume(issue)/page/year: 9,164,1973
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
250 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CBCCT* "Summary Tables of Biological Tests," National Research Council Chemical-Biological Coordination Center. (National Academy of Science Library, 2101 Constitution Ave., NW, Washington, DC 20418) Volume(issue)/page/year: 7,792,1955 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
80 mg/kg/4D-I
TOXIC EFFECTS :
Gastrointestinal - ulceration or bleeding from stomach
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 52,454,1980
Symbol GHS06
GHS06
Signal Word Danger
Hazard Statements H301-H315-H319
Precautionary Statements P301 + P310-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes Xn:Harmful
Risk Phrases R22;R36/37/38
Safety Phrases S26-S36-S37/39
RIDADR UN 2811 6.1/PG 3
WGK Germany 3
RTECS VO2080000
Packaging Group III
Hazard Class 6.1
HS Code 29182990
HS Code 2918290000
Summary HS: 2918290000 other carboxylic acids with phenol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) VAT:17.0% MFN tariff:6.5% General tariff:30.0%