61977-29-5
61977-29-5 structure
- Name: 6-Chlorobenzo[D]Isoxazol-3-Ol
- Chemical Name: 6-Chlorobenzo[d]isoxazol-3-ol
- CAS Number: 61977-29-5
- Molecular Formula: C7H4ClNO2
- Molecular Weight: 169.565
- Create Date: 2018-03-01 08:00:00
- Modify Date: 2025-08-25 10:29:15
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CBIO is a potent, cell-permeable, D-amino acid oxidase (DAO) reversible inhibitor. In rat models, CBIO prevents formalin-induced tonic pain but not acute nociception.
| Name | 6-Chlorobenzo[d]isoxazol-3-ol |
|---|---|
| Synonyms |
6-Chloro-1,2-benzoxazol-3(2H)-one
1,2-Benzisoxazol-3(2H)-one, 6-chloro- 6-chloro-1,2-benzoxazol-3-one 6-Chlorobenzo[D]Isoxazol-3-Ol |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 336.7±22.0 °C at 760 mmHg |
| Melting Point | 218-220ºC |
| Molecular Formula | C7H4ClNO2 |
| Molecular Weight | 169.565 |
| Flash Point | 157.4±22.3 °C |
| Exact Mass | 168.993057 |
| PSA | 46.26000 |
| LogP | 1.49 |
| Vapour Pressure | 0.0±0.8 mmHg at 25°C |
| Index of Refraction | 1.674 |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302 |
| Hazard Codes | Xi |
| Risk Phrases | R36/37/38 |
| Safety Phrases | 26-36/37/39 |
| RIDADR | NONH for all modes of transport |
| HS Code | 2934999090 |
|
~88%
61977-29-5 |
| Literature: Jiangsu Guohua Investment Co., Ltd; Shanghai Institute of Pharmaceutical Industry Patent: EP2322520 A1, 2011 ; Location in patent: Page/Page column 12 ; |
|
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61977-29-5 |
| Literature: US5484763 A1, ; |
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~%
61977-29-5 |
| Literature: EP2322520 A1, ; |
|
~%
61977-29-5 |
| Literature: EP2322520 A1, ; |
| Precursor 4 | |
|---|---|
| DownStream 1 | |
![3,6-Dichlorobenzo[d]isoxazole structure](https://image.chemsrc.com/caspic/189/16263-54-0.png)
| HS Code | 2934999090 |
|---|---|
| Summary | 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |