- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: 4-Chlorosalicylic acid
- Price: ￥108.0/25g ￥278.0/100g
- Purity: 98.0%
- Stocking Period: 2 Day
- Contact: Liu jia
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: 4-Chlorosalicylic acid
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Ms Wang
- Zhejiang Hangyu API Co., Ltd
- China
- Product Name: 4-Chlorosalicylic acid
- Price: ￥Inquiry/1kg
- Purity: 99.5%
- Stocking Period: Inquiry
- Contact: Vinnie
- Henan Tianfu Chemical Co., Ltd.
- China
- Product Name: 4-Chlorosalicylic acid
- Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
- Purity: 99.0%
- Stocking Period: Inquiry
- Contact: Anson
5106-98-9
5106-98-9 structure
- Name: 4-Chlorosalicylic acid
- Chemical Name: 4-Chlorosalicylic acid
- CAS Number: 5106-98-9
- Molecular Formula: C7H5ClO3
- Molecular Weight: 172.566
- Catalog: Chemical reagent Organic reagent Aromatic acid
- Create Date: 2018-02-15 08:00:00
- Modify Date: 2024-01-02 11:06:42
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4-Chlorosalicylic acid is a pharmaceutical intermediate. Inhibits monophenolase and diphenolase activity with IC50s of 1.89 mM and 1.10 mM. Potent antimicrobial activity. Against E. coli with the MIC of 250 μg/mL and with the MBC of 500 μg/mL.
| Name | 4-Chlorosalicylic acid |
|---|---|
| Synonyms |
4-Chloro Salicylic Acid
4-Chloro-2-Hydroxy Benzoic Acid MFCD00002449 Benzoic acid, 4-chloro-2-hydroxy- 4-Chlorosalicylic Acid 4-Chloro-2-hydroxybenzoic acid EINECS 225-829-7 |
| Description | 4-Chlorosalicylic acid is a pharmaceutical intermediate. Inhibits monophenolase and diphenolase activity with IC50s of 1.89 mM and 1.10 mM. Potent antimicrobial activity. Against E. coli with the MIC of 250 μg/mL and with the MBC of 500 μg/mL. |
|---|---|
| Related Catalog | |
| Target |
IC50: 1.89 mM (monophenolase), 1.10 mM (diphenolase)[1] |
| In Vitro | 4-chlorosalicylic acid could inhibit both the diphenolase activity and the monophenolase activity of mushroom tyrosinase. 4-chlorosalicylic acid has broad-spectrum antimicrobial activity which could inhibits Gram-positive and Gram-negative bacteria and fungi[1]. |
| References |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 321.1±27.0 °C at 760 mmHg |
| Melting Point | 210-212 °C(lit.) |
| Molecular Formula | C7H5ClO3 |
| Molecular Weight | 172.566 |
| Flash Point | 148.0±23.7 °C |
| Exact Mass | 171.992722 |
| PSA | 57.53000 |
| LogP | 3.14 |
| Vapour Pressure | 0.0±0.7 mmHg at 25°C |
| Index of Refraction | 1.630 |
| Water Solubility | slightly soluble |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xn:Harmful; |
| Risk Phrases | R22;R36/37/38 |
| Safety Phrases | S26-S37/39 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 2918219000 |
| Precursor 10 | |
|---|---|
| DownStream 10 | |
![6-Chlorobenzo[D]Isoxazol-3-Ol structure](https://www.chemsrc.com/caspic/066/61977-29-5.png)
![3,6-Dichlorobenzo[d]isoxazole structure](https://www.chemsrc.com/caspic/189/16263-54-0.png)
| HS Code | 2918290000 |
|---|---|
| Summary | HS: 2918290000 other carboxylic acids with phenol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) VAT:17.0% MFN tariff:6.5% General tariff:30.0% |