5106-98-9

5106-98-9 structure

Name: 4-Chlorosalicylic acid
Chemical Name: 4-Chlorosalicylic acid
CAS Number: 5106-98-9
Molecular Formula: C₇H₅ClO₃
Molecular Weight: 172.566
Catalog: Chemical reagent Organic reagent Aromatic acid
Create Date: 2018-02-15 08:00:00
Modify Date: 2025-08-22 13:20:32
4-Chlorosalicylic acid is a pharmaceutical intermediate. Inhibits monophenolase and diphenolase activity with IC50s of 1.89 mM and 1.10 mM. Potent antimicrobial activity. Against E. coli with the MIC of 250 μg/mL and with the MBC of 500 μg/mL.

Name	4-Chlorosalicylic acid
Synonyms	4-Chloro Salicylic Acid 4-Chloro-2-Hydroxy Benzoic Acid MFCD00002449 Benzoic acid, 4-chloro-2-hydroxy- 4-Chlorosalicylic Acid 4-Chloro-2-hydroxybenzoic acid EINECS 225-829-7

Description	4-Chlorosalicylic acid is a pharmaceutical intermediate. Inhibits monophenolase and diphenolase activity with IC50s of 1.89 mM and 1.10 mM. Potent antimicrobial activity. Against E. coli with the MIC of 250 μg/mL and with the MBC of 500 μg/mL.
Related Catalog	Signaling Pathways >> Anti-infection >> Bacterial Signaling Pathways >> Anti-infection >> Fungal Natural Products >> Acids and Aldehydes Research Areas >> Infection
Target	IC50: 1.89 mM (monophenolase), 1.10 mM (diphenolase)[1]
In Vitro	4-chlorosalicylic acid could inhibit both the diphenolase activity and the monophenolase activity of mushroom tyrosinase. 4-chlorosalicylic acid has broad-spectrum antimicrobial activity which could inhibits Gram-positive and Gram-negative bacteria and fungi[1].
References	[1]. Han P, et al. Inhibitory effects of 4-chlorosalicylic acid on mushroom tyrosinase and its antimicrobial activities. 107 (2), 797-803, 2008

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xn:Harmful;
Risk Phrases	R22;R36/37/38
Safety Phrases	S26-S37/39
RIDADR	NONH for all modes of transport
WGK Germany	3
HS Code	2918219000

HS Code	2918290000
Summary	HS: 2918290000 other carboxylic acids with phenol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) VAT:17.0% MFN tariff:6.5% General tariff:30.0%