72895-88-6
72895-88-6 structure
- Name: Eltenac
- Chemical Name: 2-[4-(2,6-dichloroanilino)thiophen-3-yl]acetic acid
- CAS Number: 72895-88-6
- Molecular Formula: C12H9Cl2NO2S
- Molecular Weight: 302.18
- Catalog: Signaling Pathways Immunology/Inflammation COX
- Create Date: 2018-09-09 16:11:00
- Modify Date: 2024-01-20 12:28:23
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Eltenac, a non-steroidal anti-inflammatory drug (NSAID), is a COX inhibitor. Eltenac shows IC50 of 0.03 μM for both COX-1 and COX-2 in isolated human whole blood[1].
| Name | 2-[4-(2,6-dichloroanilino)thiophen-3-yl]acetic acid |
|---|---|
| Synonyms |
4-(2,6-dichloroanilino)-3-thiophenacetic acid
Telzenac (TN) ELTENAC Eltenaco Eltenacum 4-(2,6-dichloroanilino)-3-thiopheneacetic acid [4-(2,6-dichlorophenylamino)-thiophen-3-yl] acetic acid Eltenac (INN) Telzenac Eltenaco [Spanish] Eltenacum [Latin] |
| Description | Eltenac, a non-steroidal anti-inflammatory drug (NSAID), is a COX inhibitor. Eltenac shows IC50 of 0.03 μM for both COX-1 and COX-2 in isolated human whole blood[1]. |
|---|---|
| Related Catalog | |
| Target |
COX-1:0.03 μM (IC50) COX-2:0.03 μM (IC50) |
| In Vitro | Eltenac (10 mg/kg; p.o.; Female Sprague-Dawley rats weighing150-190; rat paw edema model) efficaciously reduces the increase in paw volume by 52%[1]. |
| References |
| Density | 1.539g/cm3 |
|---|---|
| Boiling Point | 419.4ºC at 760 mmHg |
| Molecular Formula | C12H9Cl2NO2S |
| Molecular Weight | 302.18 |
| Flash Point | 207.4ºC |
| Exact Mass | 300.97300 |
| PSA | 77.57000 |
| LogP | 4.49860 |
| Index of Refraction | 1.688 |
| Hazard Codes | T+ |
|---|---|
| HS Code | 2934999090 |
| HS Code | 2934999090 |
|---|---|
| Summary | 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |