Eltenac

Modify Date: 2024-01-20 12:28:23

Eltenac Structure
Eltenac structure
Common Name Eltenac
CAS Number 72895-88-6 Molecular Weight 302.18
Density 1.539g/cm3 Boiling Point 419.4ºC at 760 mmHg
Molecular Formula C12H9Cl2NO2S Melting Point N/A
MSDS N/A Flash Point 207.4ºC

 Use of Eltenac


Eltenac, a non-steroidal anti-inflammatory drug (NSAID), is a COX inhibitor. Eltenac shows IC50 of 0.03 μM for both COX-1 and COX-2 in isolated human whole blood[1].

 Names

Name 2-[4-(2,6-dichloroanilino)thiophen-3-yl]acetic acid
Synonym More Synonyms

 Eltenac Biological Activity

Description Eltenac, a non-steroidal anti-inflammatory drug (NSAID), is a COX inhibitor. Eltenac shows IC50 of 0.03 μM for both COX-1 and COX-2 in isolated human whole blood[1].
Related Catalog
Target

COX-1:0.03 μM (IC50)

COX-2:0.03 μM (IC50)

In Vitro Eltenac (10 mg/kg; p.o.; Female Sprague-Dawley rats weighing150-190; rat paw edema model) efficaciously reduces the increase in paw volume by 52%[1].
References

[1]. Klein T,, et al. Characterization of eltenac and novel COX-2 selective thiopheneacetic acid analogues in vitro and in vivo. Biochem Pharmacol. 2008;76(6):717-725.

 Chemical & Physical Properties

Density 1.539g/cm3
Boiling Point 419.4ºC at 760 mmHg
Molecular Formula C12H9Cl2NO2S
Molecular Weight 302.18
Flash Point 207.4ºC
Exact Mass 300.97300
PSA 77.57000
LogP 4.49860
Index of Refraction 1.688

 Safety Information

Hazard Codes T+
HS Code 2934999090

 Customs

HS Code 2934999090
Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

4-(2,6-dichloroanilino)-3-thiophenacetic acid
Telzenac (TN)
ELTENAC
Eltenaco
Eltenacum
4-(2,6-dichloroanilino)-3-thiopheneacetic acid
[4-(2,6-dichlorophenylamino)-thiophen-3-yl] acetic acid
Eltenac (INN)
Telzenac
Eltenaco [Spanish]
Eltenacum [Latin]
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