Shanghai Nianxing Industrial Co., Ltd
China
Product Name: 4-Amino-5-ethoxymethyl-2-methylpyrimidine (See also A609085, HBr salt)
Price:
Purity: 95.0%
Stocking Period: 10 Day
Contact: Yang

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 4-Pyrimidinamine,5-(ethoxymethyl)-2-methyl-
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

73-66-5

73-66-5 structure

Name: 4-Pyrimidinamine,5-(ethoxymethyl)-2-methyl-
Chemical Name: 5-(ethoxymethyl)-2-methylpyrimidin-4-amine
CAS Number: 73-66-5
Molecular Formula: C₈H₁₃N₃O
Molecular Weight: 167.20800
Catalog: Chemical reagent Organic reagent Fatty ketone (including enol)
Create Date: 2016-01-20 22:38:16
Modify Date: 2024-01-09 07:04:46

Name	5-(ethoxymethyl)-2-methylpyrimidin-4-amine
Synonyms	EINECS 200-802-2 5-Aethoxymethyl-2-methyl-pyrimidin-4-ylamin 5-Ethoxymethyl-2-methylpyrimidin-4-ylamine 4-amino-5-ethoxymethyl-2-methylpyrimidine 4-Amino-2-methyl-5-ethoxymethylpyrimidine 2-Methyl-4-amino-5-<aethoxymethyl>-pyrimidin 2-methyl-4-amino-5-ethoxymethylpyrimidine

Density	1.113g/cm3
Boiling Point	276.4ºC at 760 mmHg
Molecular Formula	C₈H₁₃N₃O
Molecular Weight	167.20800
Flash Point	121ºC
Exact Mass	167.10600
PSA	61.03000
LogP	1.48490
Index of Refraction	1.544

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UV6450000

CHEMICAL NAME :: Pyrimidine, 4-amino-5-(ethoxymethyl)-2-methyl-

CAS REGISTRY NUMBER :: 73-66-5

BEILSTEIN REFERENCE NO. :: 0139361

LAST UPDATED :: 199612

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C8-H13-N3-O

MOLECULAR WEIGHT :: 167.24

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1450 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982 Volume(issue)/page/year: -,81,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 239 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982 Volume(issue)/page/year: -,81,1982 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 11 mg/m3/17W-I

TOXIC EFFECTS :: Kidney, Ureter, Bladder - other changes in urine composition Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)

REFERENCE :: TNICS* Toxicology of New Industrial Chemical Substances. English translation of TPKVAL. (USSR Academy of Medical Sciences, Meditsina, Moscow, USSR) Volume(issue)/page/year: 13,59,1973 ** REPRODUCTIVE DATA **

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

DOSE :: 11 mg/m3

SEX/DURATION :: male 17 week(s) pre-mating

TOXIC EFFECTS :: Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count)

REFERENCE :: TNICS* Toxicology of New Industrial Chemical Substances. English translation of TPKVAL. (USSR Academy of Medical Sciences, Meditsina, Moscow, USSR) Volume(issue)/page/year: 13,59,1973 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 1 mg/m3 JAN 1993

HS Code	2933599090

749835-80-1

73-66-5

Literature: Cline et al. Journal of the American Chemical Society, 1937 , vol. 59, p. 1052

5423-97-2

73-66-5

Literature: Cline et al. Journal of the American Chemical Society, 1937 , vol. 59, p. 1052

109-95-5

874-43-1

73-66-5

Literature: Hoffmann-La Roche Patent: US2480326 , 1946 ;

2141-62-0

73-66-5

Literature: Fodor et al. Zhurnal Obshchei Khimii, 1951 , vol. 21, p. 1897,1900; engl. Ausg. S. 2109, 2111 Show Details Takamizawa et al. Yakugaku Zasshi, 1958 , vol. 78, p. 637,642 Chemical and Pharmaceutical Bulletin, 1966 , vol. 14, p. 238 Chem.Abstr., 1958 , p. 18411

3699-10-3

143-37-3

73-66-5

3699-12-5

143-37-3

73-66-5

99764-73-5

124-42-5

109-94-4

73-66-5

Detail

Literature: Litvak, M. M. Pharmaceutical Chemistry Journal, 1989 , vol. 23, # 11 p. 935 - 938 Khimiko-Farmatsevticheskii Zhurnal, 1989 , vol. 23, # 11 p. 1374 - 1377

64-17-5

3699-10-3

124-42-5

141-52-6

Detail

Literature: Takamizawa; Maeda Yakugaku Zasshi, 1954 , vol. 74, p. 746 Chem.Abstr., 1955 , p. 11662 Show Details Takamizawa et al. Yakugaku Zasshi, 1958 , vol. 78, p. 637,642 Chemical and Pharmaceutical Bulletin, 1966 , vol. 14, p. 238 Chem.Abstr., 1958 , p. 18411 Show Details Takamizawa; Hirai Chemical and Pharmaceutical Bulletin, 1964 , vol. 12, p. 393,395

HS Code	2933599090
Summary	2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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