Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 6,8-Difluoro-4-pyridin-3-yl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline
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Purity: 98.0%
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1139889-93-2

1139889-93-2 structure

Name: Golgicide A
Chemical Name: (3aR,9bS)-6,8-Difluoro-4-(3-pyridinyl)-3a,4,5,9b-tetrahydro-3H-cy clopenta[c]quinoline
CAS Number: 1139889-93-2
Molecular Formula: C₁₇H₁₄F₂N₂
Molecular Weight: 284.30
Catalog: Biochemical Inhibitor Transmembrane Transporters ATPase inhibitor
Create Date: 2018-12-21 06:08:17
Modify Date: 2025-09-17 18:17:53
Golgicide A is a potent, highly specific, and reversible inhibitor of the cis-Golgi ADP-ribosylation factor guanine nucleotide exchange factors (ArfGEF), GBF1[1].

Name	(3aR,9bS)-6,8-Difluoro-4-(3-pyridinyl)-3a,4,5,9b-tetrahydro-3H-cy clopenta[c]quinoline
Synonyms	Golgicide A

Description	Golgicide A is a potent, highly specific, and reversible inhibitor of the cis-Golgi ADP-ribosylation factor guanine nucleotide exchange factors (ArfGEF), GBF1[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
Target	GBF1[1]
In Vitro	Golgicide A (GCA) is a potent and highly effective inhibitor of shiga toxin activity. Golgicide A (GCA) inhibits the effect of shiga toxin on protein synthesis with an IC50 of 3.3 μM[1].
References	[1]. Sáenz JB, et al. Golgicide A reveals essential roles for GBF1 in Golgi assembly and function. Nat Chem Biol. 2009 Mar;5(3):157-65.