Golgicide A

Modify Date: 2024-01-06 20:36:27

Golgicide A Structure
Golgicide A structure
Common Name Golgicide A
CAS Number 1139889-93-2 Molecular Weight 284.30
Density N/A Boiling Point N/A
Molecular Formula C17H14F2N2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Golgicide A


Golgicide A is a potent, highly specific, and reversible inhibitor of the cis-Golgi ADP-ribosylation factor guanine nucleotide exchange factors (ArfGEF), GBF1[1].

 Names

Name (3aR,9bS)-6,8-Difluoro-4-(3-pyridinyl)-3a,4,5,9b-tetrahydro-3H-cy clopenta[c]quinoline
Synonym More Synonyms

 Golgicide A Biological Activity

Description Golgicide A is a potent, highly specific, and reversible inhibitor of the cis-Golgi ADP-ribosylation factor guanine nucleotide exchange factors (ArfGEF), GBF1[1].
Related Catalog
Target

GBF1[1]

In Vitro Golgicide A (GCA) is a potent and highly effective inhibitor of shiga toxin activity. Golgicide A (GCA) inhibits the effect of shiga toxin on protein synthesis with an IC50 of 3.3 μM[1].
References

[1]. Sáenz JB, et al. Golgicide A reveals essential roles for GBF1 in Golgi assembly and function. Nat Chem Biol. 2009 Mar;5(3):157-65.

 Chemical & Physical Properties

Molecular Formula C17H14F2N2
Molecular Weight 284.30
Exact Mass 284.11300
PSA 24.92000
LogP 4.32430
Storage condition Store at RT

 Synonyms

Golgicide A
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  • DC Chemicals Limited
  • China
  • Product Name: Golgicide A
  • Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao


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Price: ¥1900/5 mg

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