256461-79-7

256461-79-7 structure

Name: FR234938
Chemical Name: 1-[(3R,4S)-4-hydroxy-1-naphthalen-1-ylpentan-3-yl]imidazole-4-carboxamide
CAS Number: 256461-79-7
Molecular Formula: C₁₉H₂₁N₃O₂
Molecular Weight: 323.39
Catalog: Signaling Pathways Metabolic Enzyme/Protease Adenosine Deaminase
Create Date: 2017-05-30 22:56:17
Modify Date: 2024-01-02 19:45:20
FR234938 is a non-nucleoside adenosine deaminase inhibitor with an IC50 of 17 nM for recombinant human adenosine deaminase enzyme. FR234938 has anti-rheumatic and anti-inflammatory effects[1].

Name	1-[(3R,4S)-4-hydroxy-1-naphthalen-1-ylpentan-3-yl]imidazole-4-carboxamide
Synonyms	1H-Imidazole-4-carboxamide,1-((1R,2S)-2-hydroxy-1-(2-(1-naphthalenyl)ethyl)propyl) imidazole-4-carboxamide analogue,5 2e1w

Description	FR234938 is a non-nucleoside adenosine deaminase inhibitor with an IC50 of 17 nM for recombinant human adenosine deaminase enzyme. FR234938 has anti-rheumatic and anti-inflammatory effects[1].
Related Catalog	Research Areas >> Inflammation/Immunology Signaling Pathways >> Metabolic Enzyme/Protease >> Adenosine Deaminase
Target	IC50: 17 nM (recombinant human adenosine deaminase)[1]
References	[1]. Masako Kuno, et al. Anti-inflammatory activity of non-nucleoside adenosine deaminase inhibitor FR234938. Eur J Pharmacol. 2006 Mar 18;534(1-3):241-9.