FR234938

Modify Date: 2024-01-02 19:45:20

FR234938 Structure
FR234938 structure
Common Name FR234938
CAS Number 256461-79-7 Molecular Weight 323.39
Density N/A Boiling Point N/A
Molecular Formula C19H21N3O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of FR234938


FR234938 is a non-nucleoside adenosine deaminase inhibitor with an IC50 of 17 nM for recombinant human adenosine deaminase enzyme. FR234938 has anti-rheumatic and anti-inflammatory effects[1].

 Names

Name 1-[(3R,4S)-4-hydroxy-1-naphthalen-1-ylpentan-3-yl]imidazole-4-carboxamide
Synonym More Synonyms

 FR234938 Biological Activity

Description FR234938 is a non-nucleoside adenosine deaminase inhibitor with an IC50 of 17 nM for recombinant human adenosine deaminase enzyme. FR234938 has anti-rheumatic and anti-inflammatory effects[1].
Related Catalog
Target

IC50: 17 nM (recombinant human adenosine deaminase)[1]

References

[1]. Masako Kuno, et al. Anti-inflammatory activity of non-nucleoside adenosine deaminase inhibitor FR234938. Eur J Pharmacol. 2006 Mar 18;534(1-3):241-9.  

 Chemical & Physical Properties

Molecular Formula C19H21N3O2
Molecular Weight 323.39
Exact Mass 323.16300
PSA 82.13000
LogP 3.57410

 Synonyms

1H-Imidazole-4-carboxamide,1-((1R,2S)-2-hydroxy-1-(2-(1-naphthalenyl)ethyl)propyl)
imidazole-4-carboxamide analogue,5
2e1w
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