161262-45-9
161262-45-9 structure
- Name: Amotosalen hydrochloride
- Chemical Name: 3-(2-aminoethoxymethyl)-2,5,9-trimethylfuro[3,2-g]chromen-7-one,hydrochloride
- CAS Number: 161262-45-9
- Molecular Formula: C17H21Cl2NO4
- Molecular Weight: 337.79800
- Catalog: Research Areas Inflammation/Immunology
- Create Date: 2017-02-22 05:46:11
- Modify Date: 2024-01-02 19:22:08
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Amotosalen hydrochloride (S-59) is a light-activated, DNA-, RNA-crosslinking psoralen compound, which is used to neutralise pathogens[1].
| Name | 3-(2-aminoethoxymethyl)-2,5,9-trimethylfuro[3,2-g]chromen-7-one,hydrochloride |
|---|---|
| Synonyms |
Amotosalen hydrochloride (USAN)
Amotosalen HCl S-59 7H-Furo(3,2-g)(1)benzopyran-7-one,3-((2-aminoethoxy)methyl)-2,5,9-trimethyl-,hydrochloride Amotosalen hydrochloride 4'(4-amino-2-oxa)butyl-4,5',8-trimethylpsoralen Hydrochloride |
| Description | Amotosalen hydrochloride (S-59) is a light-activated, DNA-, RNA-crosslinking psoralen compound, which is used to neutralise pathogens[1]. |
|---|---|
| Related Catalog | |
| In Vitro | When activated by light, Amotosalen binds to the nucleic acid of the pathogen and prevents replication. Light-activated Amotosalen binds and permanently crosslinks DNA, preventing replication and thus stopping proliferation of donor T cells[1]. |
| References |
| Boiling Point | 488.8ºC at 760mmHg |
|---|---|
| Molecular Formula | C17H21Cl2NO4 |
| Molecular Weight | 337.79800 |
| Flash Point | 249.4ºC |
| Exact Mass | 337.10800 |
| PSA | 78.60000 |
| LogP | 4.44200 |
| Vapour Pressure | 1.06E-09mmHg at 25°C |
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161262-45-9 |
| Literature: Cerus Corporation Patent: US6544727 B1, 2003 ; |
| Precursor 1 | |
|---|---|
| DownStream 0 | |