2922-20-5
2922-20-5 structure
- Name: Butoxamin
- Chemical Name: 2-(tert-butylamino)-1-(2,5-dimethoxyphenyl)propan-1-ol
- CAS Number: 2922-20-5
- Molecular Formula: C15H25NO3
- Molecular Weight: 267.36400
- Catalog: Signaling Pathways GPCR/G Protein Adrenergic Receptor
- Create Date: 2016-01-18 03:14:46
- Modify Date: 2024-01-16 10:24:07
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Butaxamine (Butoxamin) is a potent, selective and orally active β2-adrenoceptor antagonist. Butaxamine shows antiosteoporotic activity[1].
| Name | 2-(tert-butylamino)-1-(2,5-dimethoxyphenyl)propan-1-ol |
|---|---|
| Synonyms |
Butaxaminum
Butaxamina Butaxamin Butaxamine |
| Description | Butaxamine (Butoxamin) is a potent, selective and orally active β2-adrenoceptor antagonist. Butaxamine shows antiosteoporotic activity[1]. |
|---|---|
| Related Catalog | |
| Target |
β2 adrenoceptor |
| In Vivo | Butaxamine (0.1, 1, 10 mg/kg; p.o.; once daily for 12 weeks) 增加大鼠的骨量指数以及强度和韧性的生物力学参数[1]。 Animal Model: Seven-week-old male SHR/Izm and WKY/Izm rats[1] Dosage: 0.1, 1, 10 mg/kg Administration: P.o.; once daily for 12 weeks Result: Prevented a decrease in bone mass and an increase in biomechanical fragility developing in SHR, suppressed both a decrease in bone formation and an increase in bone resorption in SHR. |
| References |
| Density | 1.027g/cm3 |
|---|---|
| Boiling Point | 391ºC at 760 mmHg |
| Molecular Formula | C15H25NO3 |
| Molecular Weight | 267.36400 |
| Flash Point | 190.3ºC |
| Exact Mass | 267.18300 |
| PSA | 50.72000 |
| LogP | 2.90470 |
| Vapour Pressure | 8.18E-07mmHg at 25°C |
| Index of Refraction | 1.506 |
| HS Code | 2922509090 |
|---|
| HS Code | 2922509090 |
|---|---|
| Summary | 2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |