Butoxamin

Modify Date: 2025-08-24 21:17:31

Butoxamin Structure
Butoxamin structure
Common Name Butoxamin
CAS Number 2922-20-5 Molecular Weight 267.36400
Density 1.027g/cm3 Boiling Point 391ºC at 760 mmHg
Molecular Formula C15H25NO3 Melting Point N/A
MSDS N/A Flash Point 190.3ºC

 Use of Butoxamin


Butaxamine (Butoxamin) is a potent, selective and orally active β2-adrenoceptor antagonist. Butaxamine shows antiosteoporotic activity[1].

 Names

Name 2-(tert-butylamino)-1-(2,5-dimethoxyphenyl)propan-1-ol
Synonym More Synonyms

 Butoxamin Biological Activity

Description Butaxamine (Butoxamin) is a potent, selective and orally active β2-adrenoceptor antagonist. Butaxamine shows antiosteoporotic activity[1].
Related Catalog
Target

β2 adrenoceptor

In Vivo Butaxamine (0.1, 1, 10 mg/kg; p.o.; once daily for 12 weeks) 增加大鼠的骨量指数以及强度和韧性的生物力学参数[1]。 Animal Model: Seven-week-old male SHR/Izm and WKY/Izm rats[1] Dosage: 0.1, 1, 10 mg/kg Administration: P.o.; once daily for 12 weeks Result: Prevented a decrease in bone mass and an increase in biomechanical fragility developing in SHR, suppressed both a decrease in bone formation and an increase in bone resorption in SHR.
References

[1]. Arai M, et al. Dose effects of butoxamine, a selective β2-adrenoceptor antagonist, on bone metabolism in spontaneously hypertensive rat. Eur J Pharmacol. 2013 Feb 15;701(1-3):7-13.  

 Chemical & Physical Properties

Density 1.027g/cm3
Boiling Point 391ºC at 760 mmHg
Molecular Formula C15H25NO3
Molecular Weight 267.36400
Flash Point 190.3ºC
Exact Mass 267.18300
PSA 50.72000
LogP 2.90470
Vapour Pressure 8.18E-07mmHg at 25°C
Index of Refraction 1.506

 Safety Information

HS Code 2922509090

 Customs

HS Code 2922509090
Summary 2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Synonyms

Butaxaminum
Butaxamina
Butaxamin
Butaxamine
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